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Time-dependent specific molecular signatures of inflammation and remodelling are associated with trimethylamine-N-oxide (TMAO)-induced endothelial cell dysfunction

Endothelial dysfunction is a critical initiating factor contributing to cardiovascular diseases, involving the gut microbiome-derived metabolite trimethylamine N-oxide (TMAO). This study aims to clarify the time-dependent molecular pathways by which TMAO mediates endothelial dysfunction through tran...

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Detalles Bibliográficos
Autores principales:	Shanmugham, Meyammai, Devasia, Arun George, Chin, Yu Ling, Cheong, Kang Hao, Ong, Eng Shi, Bellanger, Sophie, Ramasamy, Adaikalavan, Leo, Chen Huei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661905/ https://www.ncbi.nlm.nih.gov/pubmed/37985702 http://dx.doi.org/10.1038/s41598-023-46820-7

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