Cargando…

A temperature-dependent virus-binding assay reveals the presence of neutralizing antibodies in human cytomegalovirus gB vaccine recipients’ sera

Human cytomegalovirus (HCMV) remains an important cause of mortality in immune-compromised transplant patients and following congenital infection. Such is the burden, an effective vaccine strategy is considered to be of the highest priority. The most successful vaccines to date have focused on gener...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gomes, Ariane C., Baraniak, Ilona A., McIntosh, Megan R., Sodi, Isabella, Langstone, Toby, Siddiqui, Saima, Atkinson, Claire, McLean, Gary R., Griffiths, Paul D., Reeves, Matthew B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Microbiology Society 2023
Materias:	Animal
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661908/ https://www.ncbi.nlm.nih.gov/pubmed/37310000 http://dx.doi.org/10.1099/jgv.0.001860

Ejemplares similares

Seronegative patients vaccinated with cytomegalovirus gB-MF59 vaccine have evidence of neutralising antibody responses against gB early post-transplantation
por: Baraniak, Ilona, et al.
Publicado: (2019)

IgA binds to the AD‐2 epitope of glycoprotein B and neutralizes human cytomegalovirus
por: Siddiqui, Saima, et al.
Publicado: (2020)

The cytomegalovirus gB/MF59 vaccine candidate induces antibodies against an antigenic domain controlling cell-to-cell spread
por: Gomes, A. C., et al.
Publicado: (2023)

The natural history of non-human GB virus C in captive chimpanzees
por: Mohr, Emma L., et al.
Publicado: (2011)

Complement enhances in vitro neutralizing potency of antibodies to human cytomegalovirus glycoprotein B (gB) and immune sera induced by gB/MF59 vaccination
por: Li, Fengsheng, et al.
Publicado: (2017)

Little role of anti-gB antibodies in neutralizing activity of patient's sera with human cytomegalovirus (HCMV) infection.
por: Park, J. W., et al.
Publicado: (2000)

Epitope-Specific Humoral Responses to Human Cytomegalovirus Glycoprotein-B Vaccine With MF59: Anti-AD2 Levels Correlate With Protection From Viremia
por: Baraniak, Ilona, et al.
Publicado: (2018)

Rapamycin does not inhibit human cytomegalovirus reactivation from dendritic cells in vitro
por: Glover, Thomas E., et al.
Publicado: (2014)

Sequences of complete human cytomegalovirus genomes from infected cell cultures and clinical specimens
por: Cunningham, Charles, et al.
Publicado: (2010)

Sequential mutations associated with adaptation of human cytomegalovirus to growth in cell culture
por: Dargan, Derrick J., et al.
Publicado: (2010)

Human cytomegalovirus suppresses Fas expression and function
por: Seirafian, Sepehr, et al.
Publicado: (2014)

The Humoral Immune Response Against the gB Vaccine: Lessons Learnt from Protection in Solid Organ Transplantation
por: Gomes, Ariane C., et al.
Publicado: (2019)

Identification and characterization of bisbenzimide compounds that inhibit human cytomegalovirus replication
por: Falci Finardi, Nicole, et al.
Publicado: (2021)

Limited replication of human cytomegalovirus in a trophoblast cell line
por: Hyde, Kadeem, et al.
Publicado: (2021)

Glucocorticosteroids trigger reactivation of human cytomegalovirus from latently infected myeloid cells and increase the risk for HCMV infection in D+R+ liver transplant patients
por: Van Damme, Ellen, et al.
Publicado: (2015)

Human cytomegalovirus and transplantation: drug development and regulatory issues
por: McIntosh, Megan, et al.
Publicado: (2016)

High-throughput sequence analysis of variants of human cytomegalovirus strains Towne and AD169
por: Bradley, Amanda J., et al.
Publicado: (2009)

Regulation of host and viral promoters during human cytomegalovirus latency via US28 and CTCF
por: Elder, Elizabeth G., et al.
Publicado: (2021)

Regulation of the subcellular distribution of key cellular RNA-processing factors during permissive human cytomegalovirus infection
por: Gaddy, Charla E., et al.
Publicado: (2010)

Human cytomegalovirus transcriptome activity differs during replication in human fibroblast, epithelial and astrocyte cell lines
por: Towler, James C., et al.
Publicado: (2012)

Sexual dimorphism in the Arachnid orders
por: McLean, Callum J., et al.
Publicado: (2018)

Human cytomegalovirus UL141 promotes efficient downregulation of the natural killer cell activating ligand CD112
por: Prod'homme, Virginie, et al.
Publicado: (2010)

Src family kinase activity drives cytomegalovirus reactivation by recruiting MOZ histone acetyltransferase activity to the viral promoter
por: Dupont, Liane, et al.
Publicado: (2019)

Rationally designed Human Cytomegalovirus gB nanoparticle vaccine with improved immunogenicity
por: Perotti, Michela, et al.
Publicado: (2020)

Association of human cytomegalovirus proteins IRS1 and TRS1 with the viral DNA polymerase accessory subunit UL44
por: Strang, Blair L., et al.
Publicado: (2010)

Interaction of the human cytomegalovirus uracil DNA glycosylase UL114 with the viral DNA polymerase catalytic subunit UL54
por: Strang, Blair L., et al.
Publicado: (2010)

Intraspecific body size variation and allometry of genitalia in the orb-web spider—Argiope lobata
por: Dharmarathne, Chathuranga, et al.
Publicado: (2023)

Murine cytomegalovirus major immediate-early protein 3 interacts with cellular and viral proteins in viral DNA replication compartments and is important for early gene activation
por: Martínez, Francisco Puerta, et al.
Publicado: (2010)

Using accelerometers to develop time-energy budgets of wild fur seals from captive surrogates
por: Ladds, Monique A., et al.
Publicado: (2018)

Impact of rising sea levels on Australian fur seals
por: McLean, Lachlan J., et al.
Publicado: (2018)

Novel decorating behaviour of silk retreats in a challenging habitat
por: Aceves-Aparicio, Alfonso, et al.
Publicado: (2022)

Novel protective role for MAP kinase phosphatase 2 in inflammatory arthritis
por: Schroeder, Juliane, et al.
Publicado: (2019)

1113 Safety and Efficacy of a Cytomegalovirus Glycoprotein B (gB) Vaccine in Adolescent Girls
por: Bernstein, David I., et al.
Publicado: (2014)

Pathogenesis of human cytomegalovirus in the immunocompromised host
por: Griffiths, Paul, et al.
Publicado: (2021)

Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4(+) CTL
por: Hegde, Nagendra R., et al.
Publicado: (2005)

Training of Lived Experience Workforces: A Rapid Review of Content and Outcomes
por: Opie, Jessica E., et al.
Publicado: (2022)

NK Cell Memory to Cytomegalovirus: Implications for Vaccine Development
por: Forrest, Calum, et al.
Publicado: (2020)

Human Cytomegalovirus gH/gL Forms a Stable Complex with the Fusion Protein gB in Virions
por: Vanarsdall, Adam L., et al.
Publicado: (2016)

A gB/CD3 bispecific BiTE antibody construct for targeting Human Cytomegalovirus-infected cells
por: Brey, Charlotte U., et al.
Publicado: (2018)

Antibody Titers Against Human Cytomegalovirus gM/gN and gB Among Pregnant Women and Their Infants
por: Talavera-Barber, Maria, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4omuoldm1lvivpbj56qn39og16