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Risk factors for patients hospitalized with recurrent colon diverticular bleeding: a single center experience

BACKGROUND/AIMS: Colonic diverticular bleeding (CDB) is a common cause of acute lower gastrointestinal bleeding. Patients with CDB are at increased risk for recurrence. Here, we aimed to evaluate the clinical course of patients with CDB and identify risk factors for recurrent CDB (rCDB). METHODS: We...

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Autores principales: You, Hye-Su, Kim, Dong Hyun, Cho, Seo-Yeon, Park, Seon-Young, Park, Chang Hwan, Kim, Hyun-Soo, Choi, Sung Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661954/
https://www.ncbi.nlm.nih.gov/pubmed/38020084
http://dx.doi.org/10.3389/fmed.2023.1195051
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author You, Hye-Su
Kim, Dong Hyun
Cho, Seo-Yeon
Park, Seon-Young
Park, Chang Hwan
Kim, Hyun-Soo
Choi, Sung Kyu
author_facet You, Hye-Su
Kim, Dong Hyun
Cho, Seo-Yeon
Park, Seon-Young
Park, Chang Hwan
Kim, Hyun-Soo
Choi, Sung Kyu
author_sort You, Hye-Su
collection PubMed
description BACKGROUND/AIMS: Colonic diverticular bleeding (CDB) is a common cause of acute lower gastrointestinal bleeding. Patients with CDB are at increased risk for recurrence. Here, we aimed to evaluate the clinical course of patients with CDB and identify risk factors for recurrent CDB (rCDB). METHODS: We included patients who were hospitalized at a single tertiary center for management of CDB between January 2005 and March 2020. A Cox proportional hazards regression analysis was performed to evaluate the risk factors of patients with rCDB as follows: model 1 adjusted by age, Charlson comorbidity index (CCI), and presence of bilateral colon diverticula; model 2 adjusted by age, CCI, and presence of left side colon diverticula; model 3 adjusted by age, CCI, and presence of sigmoid colon diverticula. RESULTS: Among 219 patients (mean age, 68.0 years; 55 females), 56 and 163 had definite and presumptive CDB, respectively. During the median period of 506 days, 62 patients (28.3%) experienced rCDB. CCI score ≥ 4 was independently associated with rCDB in models 1, 2 and 3 (all p < 0.05). Age ≥ 75 years was independently associated with rCDB in models 1 and 2 (both p < 0.05). The presence of bilateral colon and sigmoid colon diverticula were independently associated with rCDB in models 1 and 3, respectively (both p < 0.05). CONCLUSION: rCDB frequently occurred at any time in patients with previous CDB. High CCI scores and distribution of colon diverticula were associated with rCDB. Clinicians should consider a possible rCDB for a patient considering age, comorbidity, and distribution of colon diverticula.
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spelling pubmed-106619542023-11-07 Risk factors for patients hospitalized with recurrent colon diverticular bleeding: a single center experience You, Hye-Su Kim, Dong Hyun Cho, Seo-Yeon Park, Seon-Young Park, Chang Hwan Kim, Hyun-Soo Choi, Sung Kyu Front Med (Lausanne) Medicine BACKGROUND/AIMS: Colonic diverticular bleeding (CDB) is a common cause of acute lower gastrointestinal bleeding. Patients with CDB are at increased risk for recurrence. Here, we aimed to evaluate the clinical course of patients with CDB and identify risk factors for recurrent CDB (rCDB). METHODS: We included patients who were hospitalized at a single tertiary center for management of CDB between January 2005 and March 2020. A Cox proportional hazards regression analysis was performed to evaluate the risk factors of patients with rCDB as follows: model 1 adjusted by age, Charlson comorbidity index (CCI), and presence of bilateral colon diverticula; model 2 adjusted by age, CCI, and presence of left side colon diverticula; model 3 adjusted by age, CCI, and presence of sigmoid colon diverticula. RESULTS: Among 219 patients (mean age, 68.0 years; 55 females), 56 and 163 had definite and presumptive CDB, respectively. During the median period of 506 days, 62 patients (28.3%) experienced rCDB. CCI score ≥ 4 was independently associated with rCDB in models 1, 2 and 3 (all p < 0.05). Age ≥ 75 years was independently associated with rCDB in models 1 and 2 (both p < 0.05). The presence of bilateral colon and sigmoid colon diverticula were independently associated with rCDB in models 1 and 3, respectively (both p < 0.05). CONCLUSION: rCDB frequently occurred at any time in patients with previous CDB. High CCI scores and distribution of colon diverticula were associated with rCDB. Clinicians should consider a possible rCDB for a patient considering age, comorbidity, and distribution of colon diverticula. Frontiers Media S.A. 2023-11-07 /pmc/articles/PMC10661954/ /pubmed/38020084 http://dx.doi.org/10.3389/fmed.2023.1195051 Text en Copyright © 2023 You, Kim, Cho, Park, Park, Kim and Choi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
You, Hye-Su
Kim, Dong Hyun
Cho, Seo-Yeon
Park, Seon-Young
Park, Chang Hwan
Kim, Hyun-Soo
Choi, Sung Kyu
Risk factors for patients hospitalized with recurrent colon diverticular bleeding: a single center experience
title Risk factors for patients hospitalized with recurrent colon diverticular bleeding: a single center experience
title_full Risk factors for patients hospitalized with recurrent colon diverticular bleeding: a single center experience
title_fullStr Risk factors for patients hospitalized with recurrent colon diverticular bleeding: a single center experience
title_full_unstemmed Risk factors for patients hospitalized with recurrent colon diverticular bleeding: a single center experience
title_short Risk factors for patients hospitalized with recurrent colon diverticular bleeding: a single center experience
title_sort risk factors for patients hospitalized with recurrent colon diverticular bleeding: a single center experience
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661954/
https://www.ncbi.nlm.nih.gov/pubmed/38020084
http://dx.doi.org/10.3389/fmed.2023.1195051
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