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Hepatocyte-specific regulation of autophagy and inflammasome activation via MyD88 during lethal Ehrlichia infection

Hepatocytes play a crucial role in host response to infection. Ehrlichia is an obligate intracellular bacterium that causes potentially life-threatening human monocytic ehrlichiosis (HME) characterized by an initial liver injury followed by sepsis and multi-organ failure. We previously showed that i...

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Detalles Bibliográficos
Autores principales: Teymournejad, Omid, Sharma, Aditya Kumar, Abdelwahed, Mohammed, Kader, Muhamuda, Ahmed, Ibrahim, Elkafas, Hoda, Ismail, Nahed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662044/
https://www.ncbi.nlm.nih.gov/pubmed/38022511
http://dx.doi.org/10.3389/fimmu.2023.1212167