An overview of recent treatment options for primary sclerosing cholangitis

Primary sclerosing cholangitis (PSC) is a chronic hepatic dysfunction characterized by inflammatory and tissue-degenerative strictures of the biliary tree, leading to cirrhosis and cholangiocarcinoma. The pathophysiological mechanisms involve immune-mediated responses. Numerous treatment modalities...

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Autores principales: Mousavere, Ioanna, Kalampokis, Georgios, Fousekis, Fotios, Karayiannis, Peter, Baltayiannis, Gerasimos, Christodoulou, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hellenic Society of Gastroenterology 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662072/
https://www.ncbi.nlm.nih.gov/pubmed/38023975
http://dx.doi.org/10.20524/aog.2023.0834
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author Mousavere, Ioanna
Kalampokis, Georgios
Fousekis, Fotios
Karayiannis, Peter
Baltayiannis, Gerasimos
Christodoulou, Dimitrios
author_facet Mousavere, Ioanna
Kalampokis, Georgios
Fousekis, Fotios
Karayiannis, Peter
Baltayiannis, Gerasimos
Christodoulou, Dimitrios
author_sort Mousavere, Ioanna
collection PubMed
description Primary sclerosing cholangitis (PSC) is a chronic hepatic dysfunction characterized by inflammatory and tissue-degenerative strictures of the biliary tree, leading to cirrhosis and cholangiocarcinoma. The pathophysiological mechanisms involve immune-mediated responses. Numerous treatment modalities targeting the inflammatory aspects have been suggested, but a consensus on the best treatment option is lacking. This study aims to review the most up-to-date treatment options for PSC.
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spelling pubmed-106620722023-11-01 An overview of recent treatment options for primary sclerosing cholangitis Mousavere, Ioanna Kalampokis, Georgios Fousekis, Fotios Karayiannis, Peter Baltayiannis, Gerasimos Christodoulou, Dimitrios Ann Gastroenterol Review Article Primary sclerosing cholangitis (PSC) is a chronic hepatic dysfunction characterized by inflammatory and tissue-degenerative strictures of the biliary tree, leading to cirrhosis and cholangiocarcinoma. The pathophysiological mechanisms involve immune-mediated responses. Numerous treatment modalities targeting the inflammatory aspects have been suggested, but a consensus on the best treatment option is lacking. This study aims to review the most up-to-date treatment options for PSC. Hellenic Society of Gastroenterology 2023 2023-10-30 /pmc/articles/PMC10662072/ /pubmed/38023975 http://dx.doi.org/10.20524/aog.2023.0834 Text en Copyright: © Hellenic Society of Gastroenterology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Mousavere, Ioanna
Kalampokis, Georgios
Fousekis, Fotios
Karayiannis, Peter
Baltayiannis, Gerasimos
Christodoulou, Dimitrios
An overview of recent treatment options for primary sclerosing cholangitis
title An overview of recent treatment options for primary sclerosing cholangitis
title_full An overview of recent treatment options for primary sclerosing cholangitis
title_fullStr An overview of recent treatment options for primary sclerosing cholangitis
title_full_unstemmed An overview of recent treatment options for primary sclerosing cholangitis
title_short An overview of recent treatment options for primary sclerosing cholangitis
title_sort overview of recent treatment options for primary sclerosing cholangitis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662072/
https://www.ncbi.nlm.nih.gov/pubmed/38023975
http://dx.doi.org/10.20524/aog.2023.0834
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