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Nitric oxide synthase and its function in animal reproduction: an update

Nitric oxide (NO), a free radical labile gas, is involved in the regulation of various biological functions and physiological processes during animal reproduction. Recently, increasing evidence suggests that the biological role and chemical fate of NO is dependent on dynamic regulation of its biosyn...

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Autores principales: Zhang, Wei, Chen, Su juan, Guo, Li ya, Zhang, Zijing, Zhang, Jia bin, Wang, Xiao meng, Meng, Xiang bo, Zhang, Min ying, Zhang, Ke ke, Chen, Lin lin, Li, Yi wei, Wen, Yuliang, Wang, Lei, Hu, Jian he, Bai, Yue yu, Zhang, Xiao jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662090/
https://www.ncbi.nlm.nih.gov/pubmed/38028794
http://dx.doi.org/10.3389/fphys.2023.1288669
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author Zhang, Wei
Chen, Su juan
Guo, Li ya
Zhang, Zijing
Zhang, Jia bin
Wang, Xiao meng
Meng, Xiang bo
Zhang, Min ying
Zhang, Ke ke
Chen, Lin lin
Li, Yi wei
Wen, Yuliang
Wang, Lei
Hu, Jian he
Bai, Yue yu
Zhang, Xiao jian
author_facet Zhang, Wei
Chen, Su juan
Guo, Li ya
Zhang, Zijing
Zhang, Jia bin
Wang, Xiao meng
Meng, Xiang bo
Zhang, Min ying
Zhang, Ke ke
Chen, Lin lin
Li, Yi wei
Wen, Yuliang
Wang, Lei
Hu, Jian he
Bai, Yue yu
Zhang, Xiao jian
author_sort Zhang, Wei
collection PubMed
description Nitric oxide (NO), a free radical labile gas, is involved in the regulation of various biological functions and physiological processes during animal reproduction. Recently, increasing evidence suggests that the biological role and chemical fate of NO is dependent on dynamic regulation of its biosynthetic enzyme, three distinct nitric oxide synthase (NOS) according to their structure, location and function. The impact of NOS isoforms on reproductive functions need to be timely elucidated. Here, we focus on and the basic background and latest studies on the development, structure, importance inhibitor, location pattern, complex functions. Moreover, we summarize the exactly mechanisms which involved some cell signal pathways in the regulation of NOS with cellular and molecular level in the animal reproduction. Therefore, this growing research area provides the new insight into the important role of NOS male and female reproduction system. It also provides the treatment evidence on targeting NOS of reproductive regulation and diseases.
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spelling pubmed-106620902023-11-07 Nitric oxide synthase and its function in animal reproduction: an update Zhang, Wei Chen, Su juan Guo, Li ya Zhang, Zijing Zhang, Jia bin Wang, Xiao meng Meng, Xiang bo Zhang, Min ying Zhang, Ke ke Chen, Lin lin Li, Yi wei Wen, Yuliang Wang, Lei Hu, Jian he Bai, Yue yu Zhang, Xiao jian Front Physiol Physiology Nitric oxide (NO), a free radical labile gas, is involved in the regulation of various biological functions and physiological processes during animal reproduction. Recently, increasing evidence suggests that the biological role and chemical fate of NO is dependent on dynamic regulation of its biosynthetic enzyme, three distinct nitric oxide synthase (NOS) according to their structure, location and function. The impact of NOS isoforms on reproductive functions need to be timely elucidated. Here, we focus on and the basic background and latest studies on the development, structure, importance inhibitor, location pattern, complex functions. Moreover, we summarize the exactly mechanisms which involved some cell signal pathways in the regulation of NOS with cellular and molecular level in the animal reproduction. Therefore, this growing research area provides the new insight into the important role of NOS male and female reproduction system. It also provides the treatment evidence on targeting NOS of reproductive regulation and diseases. Frontiers Media S.A. 2023-11-07 /pmc/articles/PMC10662090/ /pubmed/38028794 http://dx.doi.org/10.3389/fphys.2023.1288669 Text en Copyright © 2023 Zhang, Chen, Guo, Zhang, Zhang, Wang, Meng, Zhang, Zhang, Chen, Li, Wen, Wang, Hu, Bai and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Zhang, Wei
Chen, Su juan
Guo, Li ya
Zhang, Zijing
Zhang, Jia bin
Wang, Xiao meng
Meng, Xiang bo
Zhang, Min ying
Zhang, Ke ke
Chen, Lin lin
Li, Yi wei
Wen, Yuliang
Wang, Lei
Hu, Jian he
Bai, Yue yu
Zhang, Xiao jian
Nitric oxide synthase and its function in animal reproduction: an update
title Nitric oxide synthase and its function in animal reproduction: an update
title_full Nitric oxide synthase and its function in animal reproduction: an update
title_fullStr Nitric oxide synthase and its function in animal reproduction: an update
title_full_unstemmed Nitric oxide synthase and its function in animal reproduction: an update
title_short Nitric oxide synthase and its function in animal reproduction: an update
title_sort nitric oxide synthase and its function in animal reproduction: an update
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662090/
https://www.ncbi.nlm.nih.gov/pubmed/38028794
http://dx.doi.org/10.3389/fphys.2023.1288669
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