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Nitric oxide synthase and its function in animal reproduction: an update
Nitric oxide (NO), a free radical labile gas, is involved in the regulation of various biological functions and physiological processes during animal reproduction. Recently, increasing evidence suggests that the biological role and chemical fate of NO is dependent on dynamic regulation of its biosyn...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662090/ https://www.ncbi.nlm.nih.gov/pubmed/38028794 http://dx.doi.org/10.3389/fphys.2023.1288669 |
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author | Zhang, Wei Chen, Su juan Guo, Li ya Zhang, Zijing Zhang, Jia bin Wang, Xiao meng Meng, Xiang bo Zhang, Min ying Zhang, Ke ke Chen, Lin lin Li, Yi wei Wen, Yuliang Wang, Lei Hu, Jian he Bai, Yue yu Zhang, Xiao jian |
author_facet | Zhang, Wei Chen, Su juan Guo, Li ya Zhang, Zijing Zhang, Jia bin Wang, Xiao meng Meng, Xiang bo Zhang, Min ying Zhang, Ke ke Chen, Lin lin Li, Yi wei Wen, Yuliang Wang, Lei Hu, Jian he Bai, Yue yu Zhang, Xiao jian |
author_sort | Zhang, Wei |
collection | PubMed |
description | Nitric oxide (NO), a free radical labile gas, is involved in the regulation of various biological functions and physiological processes during animal reproduction. Recently, increasing evidence suggests that the biological role and chemical fate of NO is dependent on dynamic regulation of its biosynthetic enzyme, three distinct nitric oxide synthase (NOS) according to their structure, location and function. The impact of NOS isoforms on reproductive functions need to be timely elucidated. Here, we focus on and the basic background and latest studies on the development, structure, importance inhibitor, location pattern, complex functions. Moreover, we summarize the exactly mechanisms which involved some cell signal pathways in the regulation of NOS with cellular and molecular level in the animal reproduction. Therefore, this growing research area provides the new insight into the important role of NOS male and female reproduction system. It also provides the treatment evidence on targeting NOS of reproductive regulation and diseases. |
format | Online Article Text |
id | pubmed-10662090 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-106620902023-11-07 Nitric oxide synthase and its function in animal reproduction: an update Zhang, Wei Chen, Su juan Guo, Li ya Zhang, Zijing Zhang, Jia bin Wang, Xiao meng Meng, Xiang bo Zhang, Min ying Zhang, Ke ke Chen, Lin lin Li, Yi wei Wen, Yuliang Wang, Lei Hu, Jian he Bai, Yue yu Zhang, Xiao jian Front Physiol Physiology Nitric oxide (NO), a free radical labile gas, is involved in the regulation of various biological functions and physiological processes during animal reproduction. Recently, increasing evidence suggests that the biological role and chemical fate of NO is dependent on dynamic regulation of its biosynthetic enzyme, three distinct nitric oxide synthase (NOS) according to their structure, location and function. The impact of NOS isoforms on reproductive functions need to be timely elucidated. Here, we focus on and the basic background and latest studies on the development, structure, importance inhibitor, location pattern, complex functions. Moreover, we summarize the exactly mechanisms which involved some cell signal pathways in the regulation of NOS with cellular and molecular level in the animal reproduction. Therefore, this growing research area provides the new insight into the important role of NOS male and female reproduction system. It also provides the treatment evidence on targeting NOS of reproductive regulation and diseases. Frontiers Media S.A. 2023-11-07 /pmc/articles/PMC10662090/ /pubmed/38028794 http://dx.doi.org/10.3389/fphys.2023.1288669 Text en Copyright © 2023 Zhang, Chen, Guo, Zhang, Zhang, Wang, Meng, Zhang, Zhang, Chen, Li, Wen, Wang, Hu, Bai and Zhang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Physiology Zhang, Wei Chen, Su juan Guo, Li ya Zhang, Zijing Zhang, Jia bin Wang, Xiao meng Meng, Xiang bo Zhang, Min ying Zhang, Ke ke Chen, Lin lin Li, Yi wei Wen, Yuliang Wang, Lei Hu, Jian he Bai, Yue yu Zhang, Xiao jian Nitric oxide synthase and its function in animal reproduction: an update |
title | Nitric oxide synthase and its function in animal reproduction: an update |
title_full | Nitric oxide synthase and its function in animal reproduction: an update |
title_fullStr | Nitric oxide synthase and its function in animal reproduction: an update |
title_full_unstemmed | Nitric oxide synthase and its function in animal reproduction: an update |
title_short | Nitric oxide synthase and its function in animal reproduction: an update |
title_sort | nitric oxide synthase and its function in animal reproduction: an update |
topic | Physiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662090/ https://www.ncbi.nlm.nih.gov/pubmed/38028794 http://dx.doi.org/10.3389/fphys.2023.1288669 |
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