Megakaryocyte- and erythroblast-specific cell-free DNA patterns in plasma and platelets reflect thrombopoiesis and erythropoiesis levels

Circulating cell-free DNA (cfDNA) fragments are a biological analyte with extensive utility in diagnostic medicine. Understanding the source of cfDNA and mechanisms of release is crucial for designing and interpreting cfDNA-based liquid biopsy assays. Using cell type-specific methylation markers as...

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Detalles Bibliográficos
Autores principales: Moss, Joshua, Ben-Ami, Roni, Shai, Ela, Gal-Rosenberg, Ofer, Kalish, Yosef, Klochendler, Agnes, Cann, Gordon, Glaser, Benjamin, Arad, Ariela, Shemer, Ruth, Dor, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662131/
https://www.ncbi.nlm.nih.gov/pubmed/37985773
http://dx.doi.org/10.1038/s41467-023-43310-2

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