Association of CD4-positive cell infiltration with response to vedolizumab in patients with ulcerative colitis

Not all patients with ulcerative colitis (UC) respond initially to treatment with biologic agents, and predicting their efficacy prior to treatment is difficult. Vedolizumab, a humanized monoclonal antibody against alpha 4 beta 7 (α4β7) integrin, suppresses immune cell migration by blocking the inte...

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Detalles Bibliográficos
Autores principales: Miyazaki, Haruka, Hoshi, Namiko, Ishida, Tsukasa, Nishioka, Chiharu, Ouchi, Sachiko, Shirasaka, Daisuke, Yoshie, Tomoo, Munetomo, Yoshinori, Sakamoto, Yoshio, Osuga, Tatsuya, Matsui, Saori, Hyodo, Toshiki, Denda, Tamami, Watanabe, Daisuke, Ooi, Makoto, Kodama, Yuzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662207/
https://www.ncbi.nlm.nih.gov/pubmed/37985889
http://dx.doi.org/10.1038/s41598-023-47618-3

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