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Structural modulation of insulin by hydrophobic and hydrophilic molecules

In the bloodstream, insulin interacts with various kinds of molecules, which can alter its structure and modulate its function. In this work, we have synthesized two molecules having extremely hydrophilic and hydrophobic side chains. The effects of hydrophilic and hydrophobic molecules on the bindin...

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Detalles Bibliográficos
Autores principales: Begum, Shahnaz, Parvej, Hasan, Dalui, Ramkrishna, Paul, Swarnali, Maity, Sanhita, Sepay, Nayim, Afzal, Mohd, Chandra Halder, Umesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662218/
https://www.ncbi.nlm.nih.gov/pubmed/38019994
http://dx.doi.org/10.1039/d3ra06647a