Hypobaric hypoxia induces iron mobilization from liver and spleen and increases serum iron via activation of ghrelin/GHSR1a/MAPK signalling pathway in mice

Hypobaric hypoxia (HH) exposure affects appetite and serum iron levels in both humans and animals. Thus, whether appetite-regulating ghrelin is involved in iron regulation under HH needs to be elucidated. In vivo, C57BL/6J mice were placed in a hypobaric chamber to establish a 6000-m-high altitude e...

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Detalles Bibliográficos
Autores principales: Yang, Wanping, Li, Jiayan, Hu, Jianan, Yuan, Xiaoyu, Ding, Jie, Jiang, Hui, Wang, Guohua, Luo, Qianqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662372/
https://www.ncbi.nlm.nih.gov/pubmed/37985861
http://dx.doi.org/10.1038/s41598-023-47596-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662372/
https://www.ncbi.nlm.nih.gov/pubmed/37985861
http://dx.doi.org/10.1038/s41598-023-47596-6

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