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A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei

Trypanosomes are protozoan parasites that cycle between insect and mammalian hosts and are the causative agent of sleeping sickness. Here, we describe the changes of pseudouridine (Ψ) modification on rRNA in the two life stages of the parasite using four different genome-wide approaches. CRISPR-Cas9...

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Detalles Bibliográficos
Autores principales:	Rajan, K. Shanmugha, Madmoni, Hava, Bashan, Anat, Taoka, Masato, Aryal, Saurav, Nobe, Yuko, Doniger, Tirza, Galili Kostin, Beathrice, Blumberg, Amit, Cohen-Chalamish, Smadar, Schwartz, Schraga, Rivalta, Andre, Zimmerman, Ella, Unger, Ron, Isobe, Toshiaki, Yonath, Ada, Michaeli, Shulamit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662448/ https://www.ncbi.nlm.nih.gov/pubmed/37985661 http://dx.doi.org/10.1038/s41467-023-43263-6

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