Cargando…
Identification of inhibitors targeting the energy-coupling factor (ECF) transporters
The energy-coupling factor (ECF) transporters are a family of transmembrane proteins involved in the uptake of vitamins in a wide range of bacteria. Inhibition of the activity of these proteins could reduce the viability of pathogens that depend on vitamin uptake. The central role of vitamin transpo...
Autores principales: | Diamanti, Eleonora, Souza, Paulo C. T., Setyawati, Inda, Bousis, Spyridon, Gómez, Leticia M., Swier, Lotteke J.Y.M., Shams, Atanaz, Tsarenko, Aleksei, Stanek, Weronika K., Jäger, Manuel, Marrink, Siewert J., Slotboom, Dirk J., Hirsch, Anna K. H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662466/ https://www.ncbi.nlm.nih.gov/pubmed/37985798 http://dx.doi.org/10.1038/s42003-023-05555-x |
Ejemplares similares
-
Dynamic Combinatorial Chemistry to Identify Binders of ThiT, an S‐Component of the Energy‐Coupling Factor Transporter for Thiamine
por: Monjas, Leticia, et al.
Publicado: (2017) -
In vitro reconstitution of dynamically interacting integral membrane subunits of energy-coupling factor transporters
por: Setyawati, Inda, et al.
Publicado: (2020) -
An Efficient Way to Screen Inhibitors of Energy-Coupling Factor (ECF) Transporters in a Bacterial Uptake Assay
por: Bousis, Spyridon, et al.
Publicado: (2022) -
Expulsion mechanism of the substrate-translocating subunit in ECF transporters
por: Thangaratnarajah, Chancievan, et al.
Publicado: (2023) -
An ECF-type transporter scavenges heme to overcome iron-limitation in Staphylococcus lugdunensis
por: Jochim, Angelika, et al.
Publicado: (2020)