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RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment

BACKGROUND: Regulator of G protein signaling 5 (RGS5), as a negative regulator of G protein-coupled receptor (GPCR) signaling, is highly expressed in arterial VSMCs and pericytes, which is involved in VSMC phenotypic heterogeneity and vascular remodeling in tumors. However, its role in normal and tu...

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Detalles Bibliográficos
Autores principales: Kong, Peng, Wang, Xu, Gao, Ya-Kun, Zhang, Dan-Dan, Huang, Xiao-Fu, Song, Yu, Zhang, Wen-Di, Guo, Rui-Juan, Li, Han, Han, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662775/
https://www.ncbi.nlm.nih.gov/pubmed/37986113
http://dx.doi.org/10.1186/s13062-023-00437-y