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The role of artificial neural networks in prediction of severe acute pancreatitis associated acute respiratory distress syndrome: A retrospective study

Early identification and intervention of acute respiratory distress syndrome (ARDS) are particularly important. This study aimed to construct predictive models for ARDS following severe acute pancreatitis (SAP) by artificial neural networks and logistic regression. The artificial neural networks mod...

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Autores principales: Zou, Kang, Ren, Wensen, Huang, Shu, Jiang, Jiao, Xu, Huan, Zeng, Xinyi, Zhang, Han, Peng, Yan, Lü, Muhan, Tang, Xiaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662815/
https://www.ncbi.nlm.nih.gov/pubmed/37478242
http://dx.doi.org/10.1097/MD.0000000000034399
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author Zou, Kang
Ren, Wensen
Huang, Shu
Jiang, Jiao
Xu, Huan
Zeng, Xinyi
Zhang, Han
Peng, Yan
Lü, Muhan
Tang, Xiaowei
author_facet Zou, Kang
Ren, Wensen
Huang, Shu
Jiang, Jiao
Xu, Huan
Zeng, Xinyi
Zhang, Han
Peng, Yan
Lü, Muhan
Tang, Xiaowei
author_sort Zou, Kang
collection PubMed
description Early identification and intervention of acute respiratory distress syndrome (ARDS) are particularly important. This study aimed to construct predictive models for ARDS following severe acute pancreatitis (SAP) by artificial neural networks and logistic regression. The artificial neural networks model was constructed using clinical data from 214 SAP patients. The patient cohort was randomly divided into a training set and a test set, with 149 patients allocated to the training set and 65 patients assigned to the test set. The artificial neural networks and logistic regression models were trained by the training set, and then the performance of both models was evaluated using the test set. The sensitivity, specificity, PPV, NPV, accuracy, and AUC value of artificial neural networks model were 68.0%, 87.5%, 77.3%, 81.4%, 80.0%, 0.853 ± 0.054 (95% CI: 0.749–0.958). The sensitivity, specificity, PPV, NPV, accuracy and AUC value of logistic regression model were 48.7%, 85.3%, 65.5%, 74.4%, 72.0%, 0.799 ± 0.045 (95% CI: 0.710–0.888). There were no significant differences between the artificial neural networks and logistic regression models in predictive performance. Bedside Index of Severity in Acute Pancreatitis score, procalcitonin, prothrombin time, and serum calcium were the most important predictive variables in the artificial neural networks model. The discrimination abilities of logistic regression and artificial neural networks models in predicting SAP-related ARDS were similar. It is advisable to choose the model according to the specific research purpose.
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spelling pubmed-106628152023-07-21 The role of artificial neural networks in prediction of severe acute pancreatitis associated acute respiratory distress syndrome: A retrospective study Zou, Kang Ren, Wensen Huang, Shu Jiang, Jiao Xu, Huan Zeng, Xinyi Zhang, Han Peng, Yan Lü, Muhan Tang, Xiaowei Medicine (Baltimore) 4500 Early identification and intervention of acute respiratory distress syndrome (ARDS) are particularly important. This study aimed to construct predictive models for ARDS following severe acute pancreatitis (SAP) by artificial neural networks and logistic regression. The artificial neural networks model was constructed using clinical data from 214 SAP patients. The patient cohort was randomly divided into a training set and a test set, with 149 patients allocated to the training set and 65 patients assigned to the test set. The artificial neural networks and logistic regression models were trained by the training set, and then the performance of both models was evaluated using the test set. The sensitivity, specificity, PPV, NPV, accuracy, and AUC value of artificial neural networks model were 68.0%, 87.5%, 77.3%, 81.4%, 80.0%, 0.853 ± 0.054 (95% CI: 0.749–0.958). The sensitivity, specificity, PPV, NPV, accuracy and AUC value of logistic regression model were 48.7%, 85.3%, 65.5%, 74.4%, 72.0%, 0.799 ± 0.045 (95% CI: 0.710–0.888). There were no significant differences between the artificial neural networks and logistic regression models in predictive performance. Bedside Index of Severity in Acute Pancreatitis score, procalcitonin, prothrombin time, and serum calcium were the most important predictive variables in the artificial neural networks model. The discrimination abilities of logistic regression and artificial neural networks models in predicting SAP-related ARDS were similar. It is advisable to choose the model according to the specific research purpose. Lippincott Williams & Wilkins 2023-07-21 /pmc/articles/PMC10662815/ /pubmed/37478242 http://dx.doi.org/10.1097/MD.0000000000034399 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 4500
Zou, Kang
Ren, Wensen
Huang, Shu
Jiang, Jiao
Xu, Huan
Zeng, Xinyi
Zhang, Han
Peng, Yan
Lü, Muhan
Tang, Xiaowei
The role of artificial neural networks in prediction of severe acute pancreatitis associated acute respiratory distress syndrome: A retrospective study
title The role of artificial neural networks in prediction of severe acute pancreatitis associated acute respiratory distress syndrome: A retrospective study
title_full The role of artificial neural networks in prediction of severe acute pancreatitis associated acute respiratory distress syndrome: A retrospective study
title_fullStr The role of artificial neural networks in prediction of severe acute pancreatitis associated acute respiratory distress syndrome: A retrospective study
title_full_unstemmed The role of artificial neural networks in prediction of severe acute pancreatitis associated acute respiratory distress syndrome: A retrospective study
title_short The role of artificial neural networks in prediction of severe acute pancreatitis associated acute respiratory distress syndrome: A retrospective study
title_sort role of artificial neural networks in prediction of severe acute pancreatitis associated acute respiratory distress syndrome: a retrospective study
topic 4500
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662815/
https://www.ncbi.nlm.nih.gov/pubmed/37478242
http://dx.doi.org/10.1097/MD.0000000000034399
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