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The practices of intravenous sodium bicarbonate therapy in neonatal intensive care units: A multi-country survey

A common occurrence in the neonatal intensive care unit (NICU) is metabolic acidosis. Sodium bicarbonate (SB) has been widely used, but there is insufficient evidence on how SB affects neonates in NICUs with metabolic acidosis. The worsening of intracellular acidosis, the impairment of myocardial fu...

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Autores principales: Al-Shehri, Hassan, Alqahtani, Renad, Alromih, Aroob M., Altamimi, Amal, Alshehri, Khloud, Almehaideb, Latifah, Jabari, Mosleh, Alzayed, Abdullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662854/
https://www.ncbi.nlm.nih.gov/pubmed/37478246
http://dx.doi.org/10.1097/MD.0000000000034337
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author Al-Shehri, Hassan
Alqahtani, Renad
Alromih, Aroob M.
Altamimi, Amal
Alshehri, Khloud
Almehaideb, Latifah
Jabari, Mosleh
Alzayed, Abdullah
author_facet Al-Shehri, Hassan
Alqahtani, Renad
Alromih, Aroob M.
Altamimi, Amal
Alshehri, Khloud
Almehaideb, Latifah
Jabari, Mosleh
Alzayed, Abdullah
author_sort Al-Shehri, Hassan
collection PubMed
description A common occurrence in the neonatal intensive care unit (NICU) is metabolic acidosis. Sodium bicarbonate (SB) has been widely used, but there is insufficient evidence on how SB affects neonates in NICUs with metabolic acidosis. The worsening of intracellular acidosis, the impairment of myocardial function, fluctuations in cerebral blood flow, and intracranial hemorrhage are some of the unfavorable effects of SB treatment in neonates that have been documented in the literature. This study aimed to explore neonatologists’ practices for using intravenous SB (ISB) in NICUs. A multi-country survey was carried out in 2022 using an online questionnaire sent to neonatologists in various countries in order to gather information about the use of ISB in NICUs. A previously validated questionnaire was adapted and used in this study. The response rate was 67%. The findings show that 91.2% of neonatologists were using SB to correct metabolic acidosis in the NICU; 71.4% did not have written guidelines for using sodium bicarbonate. The majority of them (78.9%) reported that dosage is included in their guidelines for the use of ISB. The findings of this study emphasize the critical importance of providing guidelines in using ISB for managing metabolic acidosis in NICU to standardize procedures and reduce the use of potentially unsuitable and unsafe treatments, as it has been shown that 71.4% of neonatologists worldwide use sodium bicarbonate without guidelines.
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spelling pubmed-106628542023-07-21 The practices of intravenous sodium bicarbonate therapy in neonatal intensive care units: A multi-country survey Al-Shehri, Hassan Alqahtani, Renad Alromih, Aroob M. Altamimi, Amal Alshehri, Khloud Almehaideb, Latifah Jabari, Mosleh Alzayed, Abdullah Medicine (Baltimore) 6200 A common occurrence in the neonatal intensive care unit (NICU) is metabolic acidosis. Sodium bicarbonate (SB) has been widely used, but there is insufficient evidence on how SB affects neonates in NICUs with metabolic acidosis. The worsening of intracellular acidosis, the impairment of myocardial function, fluctuations in cerebral blood flow, and intracranial hemorrhage are some of the unfavorable effects of SB treatment in neonates that have been documented in the literature. This study aimed to explore neonatologists’ practices for using intravenous SB (ISB) in NICUs. A multi-country survey was carried out in 2022 using an online questionnaire sent to neonatologists in various countries in order to gather information about the use of ISB in NICUs. A previously validated questionnaire was adapted and used in this study. The response rate was 67%. The findings show that 91.2% of neonatologists were using SB to correct metabolic acidosis in the NICU; 71.4% did not have written guidelines for using sodium bicarbonate. The majority of them (78.9%) reported that dosage is included in their guidelines for the use of ISB. The findings of this study emphasize the critical importance of providing guidelines in using ISB for managing metabolic acidosis in NICU to standardize procedures and reduce the use of potentially unsuitable and unsafe treatments, as it has been shown that 71.4% of neonatologists worldwide use sodium bicarbonate without guidelines. Lippincott Williams & Wilkins 2023-07-21 /pmc/articles/PMC10662854/ /pubmed/37478246 http://dx.doi.org/10.1097/MD.0000000000034337 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License 4.0 (CCBY-NC) (https://creativecommons.org/licenses/by-nc/4.0/) , where it is permissible to download, share, remix, transform, and buildup the work provided it is properly cited. The work cannot be used commercially without permission from the journal.
spellingShingle 6200
Al-Shehri, Hassan
Alqahtani, Renad
Alromih, Aroob M.
Altamimi, Amal
Alshehri, Khloud
Almehaideb, Latifah
Jabari, Mosleh
Alzayed, Abdullah
The practices of intravenous sodium bicarbonate therapy in neonatal intensive care units: A multi-country survey
title The practices of intravenous sodium bicarbonate therapy in neonatal intensive care units: A multi-country survey
title_full The practices of intravenous sodium bicarbonate therapy in neonatal intensive care units: A multi-country survey
title_fullStr The practices of intravenous sodium bicarbonate therapy in neonatal intensive care units: A multi-country survey
title_full_unstemmed The practices of intravenous sodium bicarbonate therapy in neonatal intensive care units: A multi-country survey
title_short The practices of intravenous sodium bicarbonate therapy in neonatal intensive care units: A multi-country survey
title_sort practices of intravenous sodium bicarbonate therapy in neonatal intensive care units: a multi-country survey
topic 6200
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662854/
https://www.ncbi.nlm.nih.gov/pubmed/37478246
http://dx.doi.org/10.1097/MD.0000000000034337
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