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Rapid cloning-free mutagenesis of new SARS-CoV-2 variants using a novel reverse genetics platform
Reverse genetic systems enable the engineering of RNA virus genomes and are instrumental in studying RNA virus biology. With the recent outbreak of the coronavirus disease 2019 pandemic, already established methods were challenged by the large genome of severe acute respiratory syndrome coronavirus...
Autores principales: | Kipfer, Enja Tatjana, Hauser, David, Lett, Martin J, Otte, Fabian, Urda, Lorena, Zhang, Yuepeng, Lang, Christopher MR, Chami, Mohamed, Mittelholzer, Christian, Klimkait, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662946/ https://www.ncbi.nlm.nih.gov/pubmed/37988285 http://dx.doi.org/10.7554/eLife.89035 |
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