Rapid cloning-free mutagenesis of new SARS-CoV-2 variants using a novel reverse genetics platform

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Reverse genetic systems enable the engineering of RNA virus genomes and are instrumental in studying RNA virus biology. With the recent outbreak of the coronavirus disease 2019 pandemic, already established methods were challenged by the large genome of severe acute respiratory syndrome coronavirus...

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Detalles Bibliográficos
Autores principales: Kipfer, Enja Tatjana, Hauser, David, Lett, Martin J, Otte, Fabian, Urda, Lorena, Zhang, Yuepeng, Lang, Christopher MR, Chami, Mohamed, Mittelholzer, Christian, Klimkait, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10662946/
https://www.ncbi.nlm.nih.gov/pubmed/37988285
http://dx.doi.org/10.7554/eLife.89035
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