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Wound Coverage in Extensive Necrotizing Fasciitis with Chronic Liver Disease

Chronic liver disease is characterized by lowered immunity, altered hematological parameters, and poor wound healing. Surgeons may hesitate to intervene in such patients when they present with necrotizing fasciitis (NF) or misinform the patients regarding their chances of survival. This is because o...

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Autor principal: Choundappan, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663070/
https://www.ncbi.nlm.nih.gov/pubmed/38026764
http://dx.doi.org/10.1055/s-0043-1773770
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author Choundappan, M.
author_facet Choundappan, M.
author_sort Choundappan, M.
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description Chronic liver disease is characterized by lowered immunity, altered hematological parameters, and poor wound healing. Surgeons may hesitate to intervene in such patients when they present with necrotizing fasciitis (NF) or misinform the patients regarding their chances of survival. This is because of the poor nutritional state, thrombocytopaenia, and abnormal coagulation profile. However, recent guidelines show that platelet count and prothrombin time/international normalized ratio (PT-INR) do not predict postoperative bleeding. We can proceed with debridement followed by skin grafting of wounds in such patients. This will help reduce the high mortality rate of NF in cirrhotic patients.
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spelling pubmed-106630702023-09-01 Wound Coverage in Extensive Necrotizing Fasciitis with Chronic Liver Disease Choundappan, M. Indian J Plast Surg Chronic liver disease is characterized by lowered immunity, altered hematological parameters, and poor wound healing. Surgeons may hesitate to intervene in such patients when they present with necrotizing fasciitis (NF) or misinform the patients regarding their chances of survival. This is because of the poor nutritional state, thrombocytopaenia, and abnormal coagulation profile. However, recent guidelines show that platelet count and prothrombin time/international normalized ratio (PT-INR) do not predict postoperative bleeding. We can proceed with debridement followed by skin grafting of wounds in such patients. This will help reduce the high mortality rate of NF in cirrhotic patients. Thieme Medical and Scientific Publishers Pvt. Ltd. 2023-09-26 /pmc/articles/PMC10663070/ /pubmed/38026764 http://dx.doi.org/10.1055/s-0043-1773770 Text en Association of Plastic Surgeons of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Choundappan, M.
Wound Coverage in Extensive Necrotizing Fasciitis with Chronic Liver Disease
title Wound Coverage in Extensive Necrotizing Fasciitis with Chronic Liver Disease
title_full Wound Coverage in Extensive Necrotizing Fasciitis with Chronic Liver Disease
title_fullStr Wound Coverage in Extensive Necrotizing Fasciitis with Chronic Liver Disease
title_full_unstemmed Wound Coverage in Extensive Necrotizing Fasciitis with Chronic Liver Disease
title_short Wound Coverage in Extensive Necrotizing Fasciitis with Chronic Liver Disease
title_sort wound coverage in extensive necrotizing fasciitis with chronic liver disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663070/
https://www.ncbi.nlm.nih.gov/pubmed/38026764
http://dx.doi.org/10.1055/s-0043-1773770
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