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GABA(B) receptor outward currents are transiently disclosed by the convulsant 4-aminopyridine in vitro

The K(+) channel blocker 4-aminopyridine (4AP) has been extensively used to investigate the mechanisms underlying neuronal network synchronization in both in vitro and in vivo animal models of focal epilepsy. 4AP-induced effects are paralleled by an increase in both excitatory and inhibitory neurotr...

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Detalles Bibliográficos
Autores principales: Cattani, Adriano, Wang, Siyan, Lévesque, Maxime, Farmer, Jean-Pierre, Dudley, Roy William Roland, Avoli, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663127/
https://www.ncbi.nlm.nih.gov/pubmed/38020804
http://dx.doi.org/10.1016/j.crneur.2023.100117

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