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Gains in life expectancy from decreasing cardiovascular disease and cancer mortality – an analysis of 28 European countries 1995–2019

BACKGROUND: Life expectancy (LE) is an indicator of societal progress among rapidly aging populations. In recent decades, the displacement of deaths from cardiovascular disease (CVD) and cancer have been key drivers in further extending LE on the continent, though improvements vary markedly by count...

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Autores principales: Wéber, András, Laversanne, Mathieu, Nagy, Péter, Kenessey, István, Soerjomataram, Isabelle, Bray, Freddie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663201/
https://www.ncbi.nlm.nih.gov/pubmed/37676425
http://dx.doi.org/10.1007/s10654-023-01039-8
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author Wéber, András
Laversanne, Mathieu
Nagy, Péter
Kenessey, István
Soerjomataram, Isabelle
Bray, Freddie
author_facet Wéber, András
Laversanne, Mathieu
Nagy, Péter
Kenessey, István
Soerjomataram, Isabelle
Bray, Freddie
author_sort Wéber, András
collection PubMed
description BACKGROUND: Life expectancy (LE) is an indicator of societal progress among rapidly aging populations. In recent decades, the displacement of deaths from cardiovascular disease (CVD) and cancer have been key drivers in further extending LE on the continent, though improvements vary markedly by country, sex, and over time. This study provides a comparative overview of the age-specific contributions of CVD and cancer to increasing LE in the 27 European Union member states, plus the U.K. METHODS: Cause-by-age decompositions of national changes in LE were conducted for the years 1995–1999 and 2015–2019 based on the standard approach of multiple decrement life tables to quantify the relative impact over time. The contributions of CVD and cancer mortality changes to differences in LE were computed by sex and age for each of the 28 countries. We examine the difference between the member states before 2004 (“founding countries”) and those which accessed the EU after 2004 (“A10 countries”). RESULTS: Among men, declines in CVD mortality in the founding countries of the EU were larger contributors to increasing LE over the last decades than malignant neoplasms: 2.26 years were gained by CVD declines versus 1.07 years for cancer, with 2.23 and 0.84 years gained in A10 countries, respectively. Among women in founding countries, 1.81 and 0.54 additional life years were attributable to CVD and cancer mortality declines, respectively, while in A10 countries, the corresponding values were 2.33 and 0.37 years. Lung and stomach cancer in men, and breast cancer in women were key drivers of gains in LE due to cancer overall, though rising mortality rates from lung cancer diminished the potential impact of increasing female LE in both EU founding (e.g., France, Spain, and Sweden) and A10 countries (e.g., Croatia, Hungary, and Slovenia), notably among cohorts aged 55–70 years. Over the 25 years, the LE gap between the two sets of countries narrowed from 6.22 to 5.59 years in men, and from 4.03 to 3.12 years for women, with diminishing female mortality from CVD as a determinative contributor. CONCLUSION: This study underscores the continued existence of an East-West divide in life expectancy across the EU27 + 1, evident on benchmarking the founding vs. A10 countries. In EU founding countries, continuous economic growth alongside improved health care, health promotion and protection policies have contributed to steady declines in mortality from chronic diseases, leading to increases in life expectancy. In contrast, less favourable mortality trends in the EU A10 countries indicate greater economic and health care challenges, and a failure to implement effective health policies. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10654-023-01039-8.
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spelling pubmed-106632012023-09-07 Gains in life expectancy from decreasing cardiovascular disease and cancer mortality – an analysis of 28 European countries 1995–2019 Wéber, András Laversanne, Mathieu Nagy, Péter Kenessey, István Soerjomataram, Isabelle Bray, Freddie Eur J Epidemiol Mortality BACKGROUND: Life expectancy (LE) is an indicator of societal progress among rapidly aging populations. In recent decades, the displacement of deaths from cardiovascular disease (CVD) and cancer have been key drivers in further extending LE on the continent, though improvements vary markedly by country, sex, and over time. This study provides a comparative overview of the age-specific contributions of CVD and cancer to increasing LE in the 27 European Union member states, plus the U.K. METHODS: Cause-by-age decompositions of national changes in LE were conducted for the years 1995–1999 and 2015–2019 based on the standard approach of multiple decrement life tables to quantify the relative impact over time. The contributions of CVD and cancer mortality changes to differences in LE were computed by sex and age for each of the 28 countries. We examine the difference between the member states before 2004 (“founding countries”) and those which accessed the EU after 2004 (“A10 countries”). RESULTS: Among men, declines in CVD mortality in the founding countries of the EU were larger contributors to increasing LE over the last decades than malignant neoplasms: 2.26 years were gained by CVD declines versus 1.07 years for cancer, with 2.23 and 0.84 years gained in A10 countries, respectively. Among women in founding countries, 1.81 and 0.54 additional life years were attributable to CVD and cancer mortality declines, respectively, while in A10 countries, the corresponding values were 2.33 and 0.37 years. Lung and stomach cancer in men, and breast cancer in women were key drivers of gains in LE due to cancer overall, though rising mortality rates from lung cancer diminished the potential impact of increasing female LE in both EU founding (e.g., France, Spain, and Sweden) and A10 countries (e.g., Croatia, Hungary, and Slovenia), notably among cohorts aged 55–70 years. Over the 25 years, the LE gap between the two sets of countries narrowed from 6.22 to 5.59 years in men, and from 4.03 to 3.12 years for women, with diminishing female mortality from CVD as a determinative contributor. CONCLUSION: This study underscores the continued existence of an East-West divide in life expectancy across the EU27 + 1, evident on benchmarking the founding vs. A10 countries. In EU founding countries, continuous economic growth alongside improved health care, health promotion and protection policies have contributed to steady declines in mortality from chronic diseases, leading to increases in life expectancy. In contrast, less favourable mortality trends in the EU A10 countries indicate greater economic and health care challenges, and a failure to implement effective health policies. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10654-023-01039-8. Springer Netherlands 2023-09-07 2023 /pmc/articles/PMC10663201/ /pubmed/37676425 http://dx.doi.org/10.1007/s10654-023-01039-8 Text en © The Author(s) 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Mortality
Wéber, András
Laversanne, Mathieu
Nagy, Péter
Kenessey, István
Soerjomataram, Isabelle
Bray, Freddie
Gains in life expectancy from decreasing cardiovascular disease and cancer mortality – an analysis of 28 European countries 1995–2019
title Gains in life expectancy from decreasing cardiovascular disease and cancer mortality – an analysis of 28 European countries 1995–2019
title_full Gains in life expectancy from decreasing cardiovascular disease and cancer mortality – an analysis of 28 European countries 1995–2019
title_fullStr Gains in life expectancy from decreasing cardiovascular disease and cancer mortality – an analysis of 28 European countries 1995–2019
title_full_unstemmed Gains in life expectancy from decreasing cardiovascular disease and cancer mortality – an analysis of 28 European countries 1995–2019
title_short Gains in life expectancy from decreasing cardiovascular disease and cancer mortality – an analysis of 28 European countries 1995–2019
title_sort gains in life expectancy from decreasing cardiovascular disease and cancer mortality – an analysis of 28 european countries 1995–2019
topic Mortality
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663201/
https://www.ncbi.nlm.nih.gov/pubmed/37676425
http://dx.doi.org/10.1007/s10654-023-01039-8
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