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Baseline gene signatures of reactogenicity to Ebola vaccination: a machine learning approach across multiple cohorts
INTRODUCTION: The rVSVDG-ZEBOV-GP (Ervebo®) vaccine is both immunogenic and protective against Ebola. However, the vaccine can cause a broad range of transient adverse reactions, from headache to arthritis. Identifying baseline reactogenicity signatures can advance personalized vaccinology and incre...
Autores principales: | Gonzalez Dias Carvalho, Patrícia Conceição, Dominguez Crespo Hirata, Thiago, Mano Alves, Leandro Yukio, Moscardini, Isabelle Franco, do Nascimento, Ana Paula Barbosa, Costa-Martins, André G., Sorgi, Sara, Harandi, Ali M., Ferreira, Daniela M., Vianello, Eleonora, Haks, Mariëlle C., Ottenhoff, Tom H. M., Santoro, Francesco, Martinez-Murillo, Paola, Huttner, Angela, Siegrist, Claire-Anne, Medaglini, Donata, Nakaya, Helder I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663260/ https://www.ncbi.nlm.nih.gov/pubmed/38022684 http://dx.doi.org/10.3389/fimmu.2023.1259197 |
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