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HIV-1 Gag targeting to the plasma membrane reorganizes sphingomyelin-rich and cholesterol-rich lipid domains

Although the human immunodeficiency virus type 1 lipid envelope has been reported to be enriched with host cell sphingomyelin and cholesterol, the molecular mechanism of the enrichment is not well understood. Viral Gag protein plays a central role in virus budding. Here, we report the interaction be...

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Detalles Bibliográficos
Autores principales: Tomishige, Nario, Bin Nasim, Maaz, Murate, Motohide, Pollet, Brigitte, Didier, Pascal, Godet, Julien, Richert, Ludovic, Sako, Yasushi, Mély, Yves, Kobayashi, Toshihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663554/
https://www.ncbi.nlm.nih.gov/pubmed/37990014
http://dx.doi.org/10.1038/s41467-023-42994-w