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Effect of automated head-thorax elevation during chest compressions on lung ventilation: a model study
Our goal was to investigate the effects of head-thorax elevation (HUP) during chest compressions (CC) on lung ventilation. A prospective study was performed on seven human cadavers. Chest was automatically compressed-decompressed in flat position and during progressive HUP from 18 to 35°. Lung venti...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663599/ https://www.ncbi.nlm.nih.gov/pubmed/37989865 http://dx.doi.org/10.1038/s41598-023-47727-z |
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author | Duhem, Hélène Terzi, Nicolas Segond, Nicolas Bellier, Alexandre Sanchez, Caroline Louis, Bruno Debaty, Guillaume Guérin, Claude |
author_facet | Duhem, Hélène Terzi, Nicolas Segond, Nicolas Bellier, Alexandre Sanchez, Caroline Louis, Bruno Debaty, Guillaume Guérin, Claude |
author_sort | Duhem, Hélène |
collection | PubMed |
description | Our goal was to investigate the effects of head-thorax elevation (HUP) during chest compressions (CC) on lung ventilation. A prospective study was performed on seven human cadavers. Chest was automatically compressed-decompressed in flat position and during progressive HUP from 18 to 35°. Lung ventilation was measured with electrical impedance tomography. In each cadaver, 5 sequences were randomly performed: one without CC at positive end-expiratory pressure (PEEP) 0cmH(2)O, 3 s with CC at PEEP0, 5 or 10cmH(2)O and 1 with CC and an impedance threshold device at PEEP0cmH(2)O. The minimal-to-maximal change in impedance (VT(EIT) in arbitrary unit a.u.) and the minimal impedance in every breathing cycle (EELI) the) were compared between flat, 18°, and 35° in each sequence by a mixed-effects model. Values are expressed as median (1st–3rd quartiles). With CC, between flat, 18° and 35° VT(EIT) decreased at each level of PEEP. It was 12416a.u. (10,689; 14,442), 11,239 (7667; 13,292), and 6457 (4631; 9516), respectively, at PEEP0. The same was true with the impedance threshold device. EELI/VT(EIT) significantly decreased from − 0.30 (− 0.40; − 0.15) before to − 1.13 (− 1.70; − 0.61) after the CC (P = 0.009). With HUP lung ventilation decreased with CC as compared to flat position. CC are associated with decreased in EELI. |
format | Online Article Text |
id | pubmed-10663599 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-106635992023-11-21 Effect of automated head-thorax elevation during chest compressions on lung ventilation: a model study Duhem, Hélène Terzi, Nicolas Segond, Nicolas Bellier, Alexandre Sanchez, Caroline Louis, Bruno Debaty, Guillaume Guérin, Claude Sci Rep Article Our goal was to investigate the effects of head-thorax elevation (HUP) during chest compressions (CC) on lung ventilation. A prospective study was performed on seven human cadavers. Chest was automatically compressed-decompressed in flat position and during progressive HUP from 18 to 35°. Lung ventilation was measured with electrical impedance tomography. In each cadaver, 5 sequences were randomly performed: one without CC at positive end-expiratory pressure (PEEP) 0cmH(2)O, 3 s with CC at PEEP0, 5 or 10cmH(2)O and 1 with CC and an impedance threshold device at PEEP0cmH(2)O. The minimal-to-maximal change in impedance (VT(EIT) in arbitrary unit a.u.) and the minimal impedance in every breathing cycle (EELI) the) were compared between flat, 18°, and 35° in each sequence by a mixed-effects model. Values are expressed as median (1st–3rd quartiles). With CC, between flat, 18° and 35° VT(EIT) decreased at each level of PEEP. It was 12416a.u. (10,689; 14,442), 11,239 (7667; 13,292), and 6457 (4631; 9516), respectively, at PEEP0. The same was true with the impedance threshold device. EELI/VT(EIT) significantly decreased from − 0.30 (− 0.40; − 0.15) before to − 1.13 (− 1.70; − 0.61) after the CC (P = 0.009). With HUP lung ventilation decreased with CC as compared to flat position. CC are associated with decreased in EELI. Nature Publishing Group UK 2023-11-21 /pmc/articles/PMC10663599/ /pubmed/37989865 http://dx.doi.org/10.1038/s41598-023-47727-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Duhem, Hélène Terzi, Nicolas Segond, Nicolas Bellier, Alexandre Sanchez, Caroline Louis, Bruno Debaty, Guillaume Guérin, Claude Effect of automated head-thorax elevation during chest compressions on lung ventilation: a model study |
title | Effect of automated head-thorax elevation during chest compressions on lung ventilation: a model study |
title_full | Effect of automated head-thorax elevation during chest compressions on lung ventilation: a model study |
title_fullStr | Effect of automated head-thorax elevation during chest compressions on lung ventilation: a model study |
title_full_unstemmed | Effect of automated head-thorax elevation during chest compressions on lung ventilation: a model study |
title_short | Effect of automated head-thorax elevation during chest compressions on lung ventilation: a model study |
title_sort | effect of automated head-thorax elevation during chest compressions on lung ventilation: a model study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663599/ https://www.ncbi.nlm.nih.gov/pubmed/37989865 http://dx.doi.org/10.1038/s41598-023-47727-z |
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