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Therapeutic targeting of tumor spheroids in a 3D microphysiological renal cell carcinoma-on-a-chip system

Metastatic renal cell carcinoma (RCC) remains an incurable disease for most patients highlighting an urgent need for new treatments. However, the preclinical investigation of new therapies is limited by traditional two-dimensional (2D) cultures which do not recapitulate the properties of tumor cells...

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Detalles Bibliográficos
Autores principales: Miller, Chris P., Fung, Megan, Jaeger-Ruckstuhl, Carla A., Xu, Yuexin, Warren, Edus H., Akilesh, Shreeram, Tykodi, Scott S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663960/
https://www.ncbi.nlm.nih.gov/pubmed/37944353
http://dx.doi.org/10.1016/j.neo.2023.100948