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Therapeutic targeting of tumor spheroids in a 3D microphysiological renal cell carcinoma-on-a-chip system
Metastatic renal cell carcinoma (RCC) remains an incurable disease for most patients highlighting an urgent need for new treatments. However, the preclinical investigation of new therapies is limited by traditional two-dimensional (2D) cultures which do not recapitulate the properties of tumor cells...
Autores principales: | Miller, Chris P., Fung, Megan, Jaeger-Ruckstuhl, Carla A., Xu, Yuexin, Warren, Edus H., Akilesh, Shreeram, Tykodi, Scott S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663960/ https://www.ncbi.nlm.nih.gov/pubmed/37944353 http://dx.doi.org/10.1016/j.neo.2023.100948 |
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