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Heterologous expression of the cryptic mdk gene cluster and structural revision of maduralactomycin A

After conducting an in silico analysis of the cryptic mdk cluster region and performing transcriptomic studies, an integrative Streptomyces BAC Vector containing the mdk gene sequence was constructed. The heterologous expression of the mdk cluster in Streptomyces albus J1074 resulted in the producti...

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Detalles Bibliográficos
Autores principales:	Schwitalla, Jan W., Le, Ngoc-Thao-Hien, Um, Soohyun, Schalk, Felix, Brönstrup, Mark, Baunach, Martin, Beemelmanns, Christine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663993/ https://www.ncbi.nlm.nih.gov/pubmed/38019997 http://dx.doi.org/10.1039/d3ra05931f

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