Improved quality metrics for association and reproducibility in chromatin accessibility data using mutual information

BACKGROUND: Correlation metrics are widely utilized in genomics analysis and often implemented with little regard to assumptions of normality, homoscedasticity, and independence of values. This is especially true when comparing values between replicated sequencing experiments that probe chromatin ac...

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Detalles Bibliográficos
Autores principales: Roth, Cullen, Venu, Vrinda, Job, Vanessa, Lubbers, Nicholas, Sanbonmatsu, Karissa Y., Steadman, Christina R., Starkenburg, Shawn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664258/
https://www.ncbi.nlm.nih.gov/pubmed/37990143
http://dx.doi.org/10.1186/s12859-023-05553-0

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