Cargando…
Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study
PURPOSE: The purpose of this study was to investigate the effect of laparoscopic left colectomy (LLC) and laparoscopic sigmoidectomy (LSD) on short-term outcomes and prognosis of sigmoid colon cancer (SCC) patients using propensity score matching (PSM). METHODS: In this retrospective study, the SCC...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664434/ https://www.ncbi.nlm.nih.gov/pubmed/37982606 http://dx.doi.org/10.1177/10732748231210676 |
_version_ | 1785148735516311552 |
---|---|
author | Tao, Wei Liu, Fei Cheng, Yu-Xi Zhang, Bin Liu, Xiao-Yu Zhang, Wei Peng, Dong |
author_facet | Tao, Wei Liu, Fei Cheng, Yu-Xi Zhang, Bin Liu, Xiao-Yu Zhang, Wei Peng, Dong |
author_sort | Tao, Wei |
collection | PubMed |
description | PURPOSE: The purpose of this study was to investigate the effect of laparoscopic left colectomy (LLC) and laparoscopic sigmoidectomy (LSD) on short-term outcomes and prognosis of sigmoid colon cancer (SCC) patients using propensity score matching (PSM). METHODS: In this retrospective study, the SCC patients who underwent LLC or LSD surgery were collected from a single clinical center from Jan 2011 to Dec 2019. Short-term outcomes and prognosis were compared between patients who received LSD surgery and LLC surgery. RESULTS: A total of 356 patients were included in this study. After 1:1 PSM analysis, there were 50 patients who underwent LLC surgery and 50 patients who underwent LSD surgery left in this study. No significant difference was found in baseline characteristics after PSM (P > .05). In comparison with the LLC surgery group, the LSD surgery group had shorter operation time (P = .003) after PSM. Moreover, the surgical procedure was not an independent predictor for overall survival (OS) (P = .918, 95% CI = .333–2.688) and disease-free survival DFS (P = .730, 95% CI = .335–2.150), but age (OS: P = .009, 95% CI = 1.010–1.075; DFS: P = .014, 95% CI = 1.007–1.061) and tumor stage (OS: P = .004, 95% CI = 1.302–3.844; DFS: P < .01, 95% CI = 1.572–4.171) were the independent risk factors for OS and DFS in SCC patients. CONCLUSION: There was no significant difference between the two surgical procedures for prognosis of SCC patients. However, the possible reasons for changing the surgical procedures should be cautious by surgeons. |
format | Online Article Text |
id | pubmed-10664434 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-106644342023-11-20 Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study Tao, Wei Liu, Fei Cheng, Yu-Xi Zhang, Bin Liu, Xiao-Yu Zhang, Wei Peng, Dong Cancer Control Original Research Article PURPOSE: The purpose of this study was to investigate the effect of laparoscopic left colectomy (LLC) and laparoscopic sigmoidectomy (LSD) on short-term outcomes and prognosis of sigmoid colon cancer (SCC) patients using propensity score matching (PSM). METHODS: In this retrospective study, the SCC patients who underwent LLC or LSD surgery were collected from a single clinical center from Jan 2011 to Dec 2019. Short-term outcomes and prognosis were compared between patients who received LSD surgery and LLC surgery. RESULTS: A total of 356 patients were included in this study. After 1:1 PSM analysis, there were 50 patients who underwent LLC surgery and 50 patients who underwent LSD surgery left in this study. No significant difference was found in baseline characteristics after PSM (P > .05). In comparison with the LLC surgery group, the LSD surgery group had shorter operation time (P = .003) after PSM. Moreover, the surgical procedure was not an independent predictor for overall survival (OS) (P = .918, 95% CI = .333–2.688) and disease-free survival DFS (P = .730, 95% CI = .335–2.150), but age (OS: P = .009, 95% CI = 1.010–1.075; DFS: P = .014, 95% CI = 1.007–1.061) and tumor stage (OS: P = .004, 95% CI = 1.302–3.844; DFS: P < .01, 95% CI = 1.572–4.171) were the independent risk factors for OS and DFS in SCC patients. CONCLUSION: There was no significant difference between the two surgical procedures for prognosis of SCC patients. However, the possible reasons for changing the surgical procedures should be cautious by surgeons. SAGE Publications 2023-11-20 /pmc/articles/PMC10664434/ /pubmed/37982606 http://dx.doi.org/10.1177/10732748231210676 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Original Research Article Tao, Wei Liu, Fei Cheng, Yu-Xi Zhang, Bin Liu, Xiao-Yu Zhang, Wei Peng, Dong Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study |
title | Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study |
title_full | Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study |
title_fullStr | Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study |
title_full_unstemmed | Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study |
title_short | Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study |
title_sort | comparison of postoperative outcome and prognosis among laparoscopic left colectomy and laparoscopic sigmoidectomy in sigmoid colon cancer patients: a propensity score matching study |
topic | Original Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664434/ https://www.ncbi.nlm.nih.gov/pubmed/37982606 http://dx.doi.org/10.1177/10732748231210676 |
work_keys_str_mv | AT taowei comparisonofpostoperativeoutcomeandprognosisamonglaparoscopicleftcolectomyandlaparoscopicsigmoidectomyinsigmoidcoloncancerpatientsapropensityscorematchingstudy AT liufei comparisonofpostoperativeoutcomeandprognosisamonglaparoscopicleftcolectomyandlaparoscopicsigmoidectomyinsigmoidcoloncancerpatientsapropensityscorematchingstudy AT chengyuxi comparisonofpostoperativeoutcomeandprognosisamonglaparoscopicleftcolectomyandlaparoscopicsigmoidectomyinsigmoidcoloncancerpatientsapropensityscorematchingstudy AT zhangbin comparisonofpostoperativeoutcomeandprognosisamonglaparoscopicleftcolectomyandlaparoscopicsigmoidectomyinsigmoidcoloncancerpatientsapropensityscorematchingstudy AT liuxiaoyu comparisonofpostoperativeoutcomeandprognosisamonglaparoscopicleftcolectomyandlaparoscopicsigmoidectomyinsigmoidcoloncancerpatientsapropensityscorematchingstudy AT zhangwei comparisonofpostoperativeoutcomeandprognosisamonglaparoscopicleftcolectomyandlaparoscopicsigmoidectomyinsigmoidcoloncancerpatientsapropensityscorematchingstudy AT pengdong comparisonofpostoperativeoutcomeandprognosisamonglaparoscopicleftcolectomyandlaparoscopicsigmoidectomyinsigmoidcoloncancerpatientsapropensityscorematchingstudy |