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Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study

PURPOSE: The purpose of this study was to investigate the effect of laparoscopic left colectomy (LLC) and laparoscopic sigmoidectomy (LSD) on short-term outcomes and prognosis of sigmoid colon cancer (SCC) patients using propensity score matching (PSM). METHODS: In this retrospective study, the SCC...

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Autores principales: Tao, Wei, Liu, Fei, Cheng, Yu-Xi, Zhang, Bin, Liu, Xiao-Yu, Zhang, Wei, Peng, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664434/
https://www.ncbi.nlm.nih.gov/pubmed/37982606
http://dx.doi.org/10.1177/10732748231210676
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author Tao, Wei
Liu, Fei
Cheng, Yu-Xi
Zhang, Bin
Liu, Xiao-Yu
Zhang, Wei
Peng, Dong
author_facet Tao, Wei
Liu, Fei
Cheng, Yu-Xi
Zhang, Bin
Liu, Xiao-Yu
Zhang, Wei
Peng, Dong
author_sort Tao, Wei
collection PubMed
description PURPOSE: The purpose of this study was to investigate the effect of laparoscopic left colectomy (LLC) and laparoscopic sigmoidectomy (LSD) on short-term outcomes and prognosis of sigmoid colon cancer (SCC) patients using propensity score matching (PSM). METHODS: In this retrospective study, the SCC patients who underwent LLC or LSD surgery were collected from a single clinical center from Jan 2011 to Dec 2019. Short-term outcomes and prognosis were compared between patients who received LSD surgery and LLC surgery. RESULTS: A total of 356 patients were included in this study. After 1:1 PSM analysis, there were 50 patients who underwent LLC surgery and 50 patients who underwent LSD surgery left in this study. No significant difference was found in baseline characteristics after PSM (P > .05). In comparison with the LLC surgery group, the LSD surgery group had shorter operation time (P = .003) after PSM. Moreover, the surgical procedure was not an independent predictor for overall survival (OS) (P = .918, 95% CI = .333–2.688) and disease-free survival DFS (P = .730, 95% CI = .335–2.150), but age (OS: P = .009, 95% CI = 1.010–1.075; DFS: P = .014, 95% CI = 1.007–1.061) and tumor stage (OS: P = .004, 95% CI = 1.302–3.844; DFS: P < .01, 95% CI = 1.572–4.171) were the independent risk factors for OS and DFS in SCC patients. CONCLUSION: There was no significant difference between the two surgical procedures for prognosis of SCC patients. However, the possible reasons for changing the surgical procedures should be cautious by surgeons.
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spelling pubmed-106644342023-11-20 Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study Tao, Wei Liu, Fei Cheng, Yu-Xi Zhang, Bin Liu, Xiao-Yu Zhang, Wei Peng, Dong Cancer Control Original Research Article PURPOSE: The purpose of this study was to investigate the effect of laparoscopic left colectomy (LLC) and laparoscopic sigmoidectomy (LSD) on short-term outcomes and prognosis of sigmoid colon cancer (SCC) patients using propensity score matching (PSM). METHODS: In this retrospective study, the SCC patients who underwent LLC or LSD surgery were collected from a single clinical center from Jan 2011 to Dec 2019. Short-term outcomes and prognosis were compared between patients who received LSD surgery and LLC surgery. RESULTS: A total of 356 patients were included in this study. After 1:1 PSM analysis, there were 50 patients who underwent LLC surgery and 50 patients who underwent LSD surgery left in this study. No significant difference was found in baseline characteristics after PSM (P > .05). In comparison with the LLC surgery group, the LSD surgery group had shorter operation time (P = .003) after PSM. Moreover, the surgical procedure was not an independent predictor for overall survival (OS) (P = .918, 95% CI = .333–2.688) and disease-free survival DFS (P = .730, 95% CI = .335–2.150), but age (OS: P = .009, 95% CI = 1.010–1.075; DFS: P = .014, 95% CI = 1.007–1.061) and tumor stage (OS: P = .004, 95% CI = 1.302–3.844; DFS: P < .01, 95% CI = 1.572–4.171) were the independent risk factors for OS and DFS in SCC patients. CONCLUSION: There was no significant difference between the two surgical procedures for prognosis of SCC patients. However, the possible reasons for changing the surgical procedures should be cautious by surgeons. SAGE Publications 2023-11-20 /pmc/articles/PMC10664434/ /pubmed/37982606 http://dx.doi.org/10.1177/10732748231210676 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Research Article
Tao, Wei
Liu, Fei
Cheng, Yu-Xi
Zhang, Bin
Liu, Xiao-Yu
Zhang, Wei
Peng, Dong
Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study
title Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study
title_full Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study
title_fullStr Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study
title_full_unstemmed Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study
title_short Comparison of Postoperative Outcome and Prognosis Among Laparoscopic Left Colectomy and Laparoscopic Sigmoidectomy in Sigmoid Colon Cancer Patients: A Propensity Score Matching Study
title_sort comparison of postoperative outcome and prognosis among laparoscopic left colectomy and laparoscopic sigmoidectomy in sigmoid colon cancer patients: a propensity score matching study
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664434/
https://www.ncbi.nlm.nih.gov/pubmed/37982606
http://dx.doi.org/10.1177/10732748231210676
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