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Polystyrene nanoplastic exposure induces excessive mitophagy by activating AMPK/ULK1 pathway in differentiated SH-SY5Y cells and dopaminergic neurons in vivo

BACKGROUND: Microplastics and nanoplastics (MNPs) are emerging environmental contaminants detected in human samples, and have raised concerns regarding their potential risks to human health, particularly neurotoxicity. This study aimed to investigate the deleterious effects of polystyrene nanoplasti...

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Detalles Bibliográficos
Autores principales: Huang, Yuji, Liang, Boxuan, Li, Zhiming, Zhong, Yizhou, Wang, Bo, Zhang, Bingli, Du, Jiaxin, Ye, Rongyi, Xian, Hongyi, Min, Weicui, Yan, Xiliang, Deng, Yanhong, Feng, Yu, Bai, Ruobing, Fan, Bingchi, Yang, Xingfen, Huang, Zhenlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664492/
https://www.ncbi.nlm.nih.gov/pubmed/37993864
http://dx.doi.org/10.1186/s12989-023-00556-4