A novel intronic circular RNA circFGFR1(int2) up-regulates FGFR1 by recruiting transcriptional activators P65/FUS and suppressing miR-4687-5p to promote prostate cancer progression

Fibroblast growth factor receptor 1 (FGFR1) is a core component of the FGFs/FGFR pathway that activates multiple signalling pathways, including ERK1/2, PI3K/AKT, PLCγ, and NF-κB. Aberrant expression of FGFR1 due to gene amplification, chromosome rearrangement, point mutation, and epigenetic deregula...

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Detalles Bibliográficos
Autores principales: Wang, Ruyue, Zhong, Jinjing, Pan, Xiuyi, Su, Zhengzheng, Xu, Yunyi, Zhang, Mengni, Chen, Xueqin, Chen, Ni, Yu, Ting, Zhou, Qiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664560/
https://www.ncbi.nlm.nih.gov/pubmed/37993879
http://dx.doi.org/10.1186/s12967-023-04718-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664560/
https://www.ncbi.nlm.nih.gov/pubmed/37993879
http://dx.doi.org/10.1186/s12967-023-04718-y

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