CSPG4 CAR-redirected Cytokine Induced Killer lymphocytes (CIK) as effective cellular immunotherapy for HLA class I defective melanoma

BACKGROUND: Even acknowledging the game-changing results achieved in the treatment of metastatic melanoma with the use of immune checkpoint inhibitors (ICI), a large proportion of patients (40–60%) still fail to respond or relapse due to the development of resistance. Alterations in the expression o...

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Detalles Bibliográficos
Autores principales: Giraudo, Lidia, Cattaneo, Giulia, Gammaitoni, Loretta, Iaia, Ilenia, Donini, Chiara, Massa, Annamaria, Centomo, Maria Laura, Basiricò, Marco, Vigna, Elisa, Pisacane, Alberto, Picciotto, Franco, Berrino, Enrico, Marchiò, Caterina, Merlini, Alessandra, Paruzzo, Luca, Poletto, Stefano, Caravelli, Daniela, Biolato, Andrea Michela, Bortolot, Valentina, Landoni, Elisa, Ventin, Marco, Ferrone, Cristina R., Aglietta, Massimo, Dotti, Gianpietro, Leuci, Valeria, Carnevale-Schianca, Fabrizio, Sangiolo, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664597/
https://www.ncbi.nlm.nih.gov/pubmed/37993874
http://dx.doi.org/10.1186/s13046-023-02884-x

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