Cargando…

Liver cancer stem cell dissemination and metastasis: uncovering the role of NRCAM in hepatocellular carcinoma

BACKGROUND: Liver cancer stem cells (LCSCs) play an important role in hepatocellular carcinoma (HCC), but the mechanisms that link LCSCs to HCC metastasis remain largely unknown. This study aims to reveal the contributions of NRCAM to LCSC function and HCC metastasis, and further explore its mechani...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Lingyun, He, Linye, Liu, Chang-Hai, Qiu, Huandi, Zheng, Li, Sample, Klarke Michael, Wu, Qin, Li, Jiaxin, Xie, Kunlin, Ampuero, Javier, Li, Zhihui, Lv, Duoduo, Liu, Miao, Romero-Gómez, Manuel, Hu, Yiguo, Tang, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664624/ https://www.ncbi.nlm.nih.gov/pubmed/37993901 http://dx.doi.org/10.1186/s13046-023-02893-w

Ejemplares similares

Cataracts and NrCAM
por: Dove, Alan W.
Publicado: (2001)

The suppressive functions of Rora in B lineage cell proliferation and BCR/ABL1-induced B-ALL pathogenesis
por: Li, Ning, et al.
Publicado: (2022)

DNA repair gene expression is associated with differential prognosis between HPV16 and HPV18 positive cervical cancer patients following radiation therapy
por: Sample, Klarke M.
Publicado: (2020)

TSPAN32 suppresses chronic myeloid leukemia pathogenesis and progression by stabilizing PTEN
por: Qiu, Qiang, et al.
Publicado: (2023)

Neurofascin induces neurites by heterophilic interactions with axonal NrCAM while NrCAM requires F11 on the axonal surface to extend neurites
Publicado: (1996)

miR-505 suppresses prostate cancer progression by targeting NRCAM
por: Ling, Xiao-Hui, et al.
Publicado: (2019)

miR-505 suppresses prostate cancer progression by targeting NRCAM
por: Ling, Xiao-Hui, et al.
Publicado: (2020)

NrCAM modulates sonic hedgehog signalling by controlling smoothened translocation in the cilium
por: Basu, B, et al.
Publicado: (2015)

CHL1 and NrCAM are Primarily Expressed in Low Grade Pediatric Neuroblastoma
por: Wachowiak, Robin, et al.
Publicado: (2019)

Mapping of pituitary stress-induced gene regulation connects Nrcam to negative emotions
por: Olsen, Maria Belland, et al.
Publicado: (2022)

Examination of NRCAM, LRRN3, KIAA0716, and LAMB1 as autism candidate genes
por: Hutcheson, Holli B, et al.
Publicado: (2004)

NrCAM is a marker for substrate‐selective activation of ADAM10 in Alzheimer's disease
por: Brummer, Tobias, et al.
Publicado: (2019)

KLF9 regulates miR-338-3p/NRCAM axis to block the progression of osteosarcoma cells
por: Liu, Yunlu, et al.
Publicado: (2022)

NrCAM, a neuronal system cell-adhesion molecule, is induced in papillary thyroid carcinomas
por: Górka, B, et al.
Publicado: (2007)

Neuron Glia-Related Cell Adhesion Molecule (NrCAM) Promotes Topographic Retinocollicular Mapping
por: Dai, Jinxia, et al.
Publicado: (2013)

Expression and Function of Neuron-Glia-Related Cell Adhesion Molecule (NrCAM) in the Amygdalar Pathway
por: Mohan, Vishwa, et al.
Publicado: (2019)

NrCAM secreted by endometrial stromal cells enhances the progestin sensitivity of endometrial cancer cells through epigenetic modulation of PRB
por: Cheng, Yali, et al.
Publicado: (2022)

Targeted ablation of NrCAM or ankyrin-B results in disorganized lens fibers leading to cataract formation
por: Moré, Margret I., et al.
Publicado: (2001)

Neurocan Inhibits Semaphorin 3F Induced Dendritic Spine Remodeling Through NrCAM in Cortical Neurons
por: Mohan, Vishwa, et al.
Publicado: (2018)

Bi‐allelic loss of function variant in the NRCAM gene is associated with motor‐predominant axonal polyneuropathy; the second report
por: Elahi, Zohreh, et al.
Publicado: (2023)

Characterization of the transcriptional response of Candida parapsilosis to the antifungal peptide MAF-1A
por: Cheng, Rong, et al.
Publicado: (2020)

Tenofovir versus entecavir on the prognosis of hepatitis B-related hepatocellular carcinoma after surgical resection: a randomised controlled trial
por: Linye, He, et al.
Publicado: (2023)

Fine Mapping for Weaver Syndrome in Brown Swiss Cattle and the Identification of 41 Concordant Mutations across NRCAM, PNPLA8 and CTTNBP2
por: McClure, Matthew, et al.
Publicado: (2013)

Exosome-mediated communication in the tumor microenvironment contributes to hepatocellular carcinoma development and progression
por: Wu, Qin, et al.
Publicado: (2019)

A Direct Interaction of Axonin-1 with Ngcam-Related Cell Adhesion Molecule (Nrcam) Results in Guidance, but Not Growth of Commissural Axons
por: Fitzli, Dora, et al.
Publicado: (2000)

Association of the Neuronal Cell Adhesion Molecule (NrCAM) Gene Variants with Personality Traits and Addictive Symptoms in Methamphetamine Use Disorder
por: Yoo, Byung Kuk, et al.
Publicado: (2012)

Loss of Function of the Neural Cell Adhesion Molecule NrCAM Regulates Differentiation, Proliferation and Neurogenesis in Early Postnatal Hypothalamic Tanycytes
por: Moore, Alex, et al.
Publicado: (2022)

Emerging Regulatory Mechanisms Involved in Liver Cancer Stem Cell Properties in Hepatocellular Carcinoma
por: Lv, Duoduo, et al.
Publicado: (2021)

FLI1 Induces Megakaryopoiesis Gene Expression Through WAS/WIP-Dependent and Independent Mechanisms; Implications for Wiskott-Aldrich Syndrome
por: Wang, Chunlin, et al.
Publicado: (2021)

Genome-wide association analysis of coffee drinking suggests association with CYP1A1/CYP1A2 and NRCAM
por: Amin, N, et al.
Publicado: (2012)

Hepatocellular carcinoma with disseminated skeletal muscle metastasis
por: Rahim, Ezamin Abdul, et al.
Publicado: (2017)

Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations
por: Boru, Getachew, et al.
Publicado: (2019)

Diffuse cavernous hemangioma of the skull misdiagnosed as skull metastasis in breast cancer patient: one case report and literature review
por: Liu, Huizhi, et al.
Publicado: (2019)

TXNDC12 promotes EMT and metastasis of hepatocellular carcinoma cells via activation of β-catenin
por: Yuan, Kefei, et al.
Publicado: (2019)

FLI1 promotes protein translation via the transcriptional regulation of MKNK1 expression
por: Wang, Chunlin, et al.
Publicado: (2019)

ERK activation via A1542/3 limonoids attenuates erythroleukemia through transcriptional stimulation of cholesterol biosynthesis genes
por: Yu, Fang, et al.
Publicado: (2021)

Chemotherapy of Cancer Dissemination and Metastasis
por: Crowther, D.
Publicado: (1976)

Comparative efficacy of different ultrasound-guided ablation for the treatment of benign thyroid nodules: Systematic review and network meta-analysis of randomized controlled trials
por: He, Linye, et al.
Publicado: (2021)

Sub-micron microparticles with tunable fluorescence emission obtained via co-self-assembly of amidoximed polymeric ligands and lanthanide ions
por: Qiu, Huandi, et al.
Publicado: (2023)

Molecular composition of the node of Ranvier: identification of ankyrin- binding cell adhesion molecules neurofascin (mucin+/third FNIII domain- ) and NrCAM at nodal axon segments
Publicado: (1996)

Cannot write session to /tmp/vufind_sessions/sess_rqkr07g06dq5k3quhjo1od1f4l