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CDK5 promotes apoptosis and attenuates chemoresistance in gastric cancer via E2F1 signaling

BACKGROUND: Chemoresistance is a major clinical challenge that leads to tumor metastasis and poor clinical outcome. The mechanisms underlying gastric cancer resistance to chemotherapy are still unclear. METHODS: We conducted bioinformatics analyses of publicly available patient datasets to establish...

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Detalles Bibliográficos
Autores principales: Cao, Long-Long, Wu, Yu-Kai, Lin, Tong-Xin, Lin, Mi, Chen, Yu-Jing, Wang, Ling-Qian, Wang, Jia-Bin, Lin, Jian-Xian, Lu, Jun, Chen, Qi-Yue, Tu, Ru-Hong, Huang, Ze-Ning, Lin, Ju-Li, Zheng, Hua-Long, Xie, Jian-Wei, Li, Ping, Huang, Chang-Ming, Zheng, Chao-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664659/
https://www.ncbi.nlm.nih.gov/pubmed/37990321
http://dx.doi.org/10.1186/s12935-023-03112-4