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Inhibition of TGF-β2–Induced Trabecular Meshwork Fibrosis by Pirfenidone

PURPOSE: Trabecular meshwork (TM) fibrosis is a crucial pathophysiological process in the development of primary open-angle glaucoma. Pirfenidone (PFD) is a new, broad-spectrum antifibrotic agent approved for the treatment of idiopathic pulmonary fibrosis. This study investigated the inhibitory effe...

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Detalles Bibliográficos
Autores principales: Zhu, Xiaofeng, Zeng, Bei, Wu, Caiqing, Chen, Zidong, Yu, Minbin, Yang, Yangfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664722/
https://www.ncbi.nlm.nih.gov/pubmed/37975842
http://dx.doi.org/10.1167/tvst.12.11.21