ATM deficiency confers specific therapeutic vulnerabilities in bladder cancer

Ataxia-telangiectasia mutated (ATM) plays a central role in the cellular response to DNA damage and ATM alterations are common in several tumor types including bladder cancer. However, the specific impact of ATM alterations on therapy response in bladder cancer is uncertain. Here, we combine preclin...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Yuzhen, Börcsök, Judit, Adib, Elio, Kamran, Sophia C., Neil, Alexander J., Stawiski, Konrad, Freeman, Dory, Stormoen, Dag Rune, Sztupinszki, Zsofia, Samant, Amruta, Nassar, Amin, Bekele, Raie T., Hanlon, Timothy, Valentine, Henkel, Epstein, Ilana, Sharma, Bijaya, Felt, Kristen, Abbosh, Philip, Wu, Chin-Lee, Efstathiou, Jason A., Miyamoto, David T., Anderson, William, Szallasi, Zoltan, Mouw, Kent W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664985/
https://www.ncbi.nlm.nih.gov/pubmed/37992168
http://dx.doi.org/10.1126/sciadv.adg2263

Ejemplares similares

Ejemplares similares