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Disruption of the autism gene and chromatin regulator KDM5A alters hippocampal cell identity

Chromatin regulation plays a pivotal role in establishing and maintaining cellular identity and is one of the top pathways disrupted in autism spectrum disorder (ASD). The hippocampus, composed of distinct cell types, is often affected in patients with ASD. However, the specific hippocampal cell typ...

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Detalles Bibliográficos
Autores principales: El Hayek, Lauretta, DeVries, Darlene, Gogate, Ashlesha, Aiken, Ariel, Kaur, Kiran, Chahrour, Maria H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664992/
https://www.ncbi.nlm.nih.gov/pubmed/37992166
http://dx.doi.org/10.1126/sciadv.adi0074

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