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Disruption of the autism gene and chromatin regulator KDM5A alters hippocampal cell identity
Chromatin regulation plays a pivotal role in establishing and maintaining cellular identity and is one of the top pathways disrupted in autism spectrum disorder (ASD). The hippocampus, composed of distinct cell types, is often affected in patients with ASD. However, the specific hippocampal cell typ...
Autores principales: | El Hayek, Lauretta, DeVries, Darlene, Gogate, Ashlesha, Aiken, Ariel, Kaur, Kiran, Chahrour, Maria H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664992/ https://www.ncbi.nlm.nih.gov/pubmed/37992166 http://dx.doi.org/10.1126/sciadv.adi0074 |
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