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Cost-utility analysis of robotic arm-assisted medial compartment knee arthroplasty: five-year data from a randomized controlled trial

AIMS: To perform an incremental cost-utility analysis and assess the impact of differential costs and case volume on the cost-effectiveness of robotic arm-assisted unicompartmental knee arthroplasty (rUKA) compared to manual (mUKA). METHODS: This was a five-year follow-up study of patients who were...

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Autores principales: Clement, Nick. D., Fraser, Ewen, Gilmour, Alisdair, Doonan, James, MacLean, Angus, Jones, Bryn G., Blyth, Mark J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665097/
https://www.ncbi.nlm.nih.gov/pubmed/37992738
http://dx.doi.org/10.1302/2633-1462.411.BJO-2023-0090.R1
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author Clement, Nick. D.
Fraser, Ewen
Gilmour, Alisdair
Doonan, James
MacLean, Angus
Jones, Bryn G.
Blyth, Mark J. G.
author_facet Clement, Nick. D.
Fraser, Ewen
Gilmour, Alisdair
Doonan, James
MacLean, Angus
Jones, Bryn G.
Blyth, Mark J. G.
author_sort Clement, Nick. D.
collection PubMed
description AIMS: To perform an incremental cost-utility analysis and assess the impact of differential costs and case volume on the cost-effectiveness of robotic arm-assisted unicompartmental knee arthroplasty (rUKA) compared to manual (mUKA). METHODS: This was a five-year follow-up study of patients who were randomized to rUKA (n = 64) or mUKA (n = 65). Patients completed the EuroQol five-dimension questionnaire (EQ-5D) preoperatively, and at three months and one, two, and five years postoperatively, which was used to calculate quality-adjusted life years (QALYs) gained. Costs for the primary and additional surgery and healthcare costs were calculated. RESULTS: rUKA was associated with a relative 0.012 QALY gain at five years, which was associated with an incremental cost per QALY of £13,078 for a unit undertaking 400 cases per year. A cost per QALY of less than £20,000 was achieved when ≥ 300 cases were performed per year. However, on removal of the cost for a revision for presumed infection (mUKA group, n = 1) the cost per QALY was greater than £38,000, which was in part due to the increased intraoperative consumable costs associated with rUKA (£626 per patient). When the absolute cost difference (operative and revision costs) was less than £240, a cost per QALY of less than £20,000 was achieved. On removing the cost of the revision for infection, rUKA was cost-neutral when more than 900 cases per year were undertaken and when the consumable costs were zero. CONCLUSION: rUKA was a cost-effective intervention with an incremental cost per QALY of £13,078 at five years, however when removing the revision for presumed infection, which was arguably a random event, this was no longer the case. The absolute cost difference had to be less than £240 to be cost-effective, which could be achieved by reducing the perioperative costs of rUKA or if there were increased revision costs associated with mUKA with longer follow-up. Cite this article: Bone Jt Open 2023;4(11):889–899.
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spelling pubmed-106650972023-11-23 Cost-utility analysis of robotic arm-assisted medial compartment knee arthroplasty: five-year data from a randomized controlled trial Clement, Nick. D. Fraser, Ewen Gilmour, Alisdair Doonan, James MacLean, Angus Jones, Bryn G. Blyth, Mark J. G. Bone Jt Open Knee AIMS: To perform an incremental cost-utility analysis and assess the impact of differential costs and case volume on the cost-effectiveness of robotic arm-assisted unicompartmental knee arthroplasty (rUKA) compared to manual (mUKA). METHODS: This was a five-year follow-up study of patients who were randomized to rUKA (n = 64) or mUKA (n = 65). Patients completed the EuroQol five-dimension questionnaire (EQ-5D) preoperatively, and at three months and one, two, and five years postoperatively, which was used to calculate quality-adjusted life years (QALYs) gained. Costs for the primary and additional surgery and healthcare costs were calculated. RESULTS: rUKA was associated with a relative 0.012 QALY gain at five years, which was associated with an incremental cost per QALY of £13,078 for a unit undertaking 400 cases per year. A cost per QALY of less than £20,000 was achieved when ≥ 300 cases were performed per year. However, on removal of the cost for a revision for presumed infection (mUKA group, n = 1) the cost per QALY was greater than £38,000, which was in part due to the increased intraoperative consumable costs associated with rUKA (£626 per patient). When the absolute cost difference (operative and revision costs) was less than £240, a cost per QALY of less than £20,000 was achieved. On removing the cost of the revision for infection, rUKA was cost-neutral when more than 900 cases per year were undertaken and when the consumable costs were zero. CONCLUSION: rUKA was a cost-effective intervention with an incremental cost per QALY of £13,078 at five years, however when removing the revision for presumed infection, which was arguably a random event, this was no longer the case. The absolute cost difference had to be less than £240 to be cost-effective, which could be achieved by reducing the perioperative costs of rUKA or if there were increased revision costs associated with mUKA with longer follow-up. Cite this article: Bone Jt Open 2023;4(11):889–899. The British Editorial Society of Bone & Joint Surgery 2023-11-23 /pmc/articles/PMC10665097/ /pubmed/37992738 http://dx.doi.org/10.1302/2633-1462.411.BJO-2023-0090.R1 Text en © 2023 Blyth et al. https://creativecommons.org/licenses/by-nc-nd/4.0/https://online.boneandjoint.org.uk/TDMThis is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Knee
Clement, Nick. D.
Fraser, Ewen
Gilmour, Alisdair
Doonan, James
MacLean, Angus
Jones, Bryn G.
Blyth, Mark J. G.
Cost-utility analysis of robotic arm-assisted medial compartment knee arthroplasty: five-year data from a randomized controlled trial
title Cost-utility analysis of robotic arm-assisted medial compartment knee arthroplasty: five-year data from a randomized controlled trial
title_full Cost-utility analysis of robotic arm-assisted medial compartment knee arthroplasty: five-year data from a randomized controlled trial
title_fullStr Cost-utility analysis of robotic arm-assisted medial compartment knee arthroplasty: five-year data from a randomized controlled trial
title_full_unstemmed Cost-utility analysis of robotic arm-assisted medial compartment knee arthroplasty: five-year data from a randomized controlled trial
title_short Cost-utility analysis of robotic arm-assisted medial compartment knee arthroplasty: five-year data from a randomized controlled trial
title_sort cost-utility analysis of robotic arm-assisted medial compartment knee arthroplasty: five-year data from a randomized controlled trial
topic Knee
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665097/
https://www.ncbi.nlm.nih.gov/pubmed/37992738
http://dx.doi.org/10.1302/2633-1462.411.BJO-2023-0090.R1
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