Venom-gland transcriptomics and venom proteomics of the Tibellus oblongus spider

The Tibellus oblongus spider is an active hunter that does not spin webs and remains highly underinvestigated in terms of the venom composition. Here, we describe venom glands transcriptome and venom proteome analysis for unveiling the polypeptide composition of Tibellus oblongus spider venom. The r...

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Autores principales: Korolkova, Yuliya, Mikov, Alexander, Lobas, Anna, Solovyeva, Elizaveta, Surin, Alexey, Andreev, Yaroslav, Gorshkov, Mikhail, Kozlov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665394/
https://www.ncbi.nlm.nih.gov/pubmed/37993463
http://dx.doi.org/10.1038/s41597-023-02703-0
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author Korolkova, Yuliya
Mikov, Alexander
Lobas, Anna
Solovyeva, Elizaveta
Surin, Alexey
Andreev, Yaroslav
Gorshkov, Mikhail
Kozlov, Sergey
author_facet Korolkova, Yuliya
Mikov, Alexander
Lobas, Anna
Solovyeva, Elizaveta
Surin, Alexey
Andreev, Yaroslav
Gorshkov, Mikhail
Kozlov, Sergey
author_sort Korolkova, Yuliya
collection PubMed
description The Tibellus oblongus spider is an active hunter that does not spin webs and remains highly underinvestigated in terms of the venom composition. Here, we describe venom glands transcriptome and venom proteome analysis for unveiling the polypeptide composition of Tibellus oblongus spider venom. The resulting EST database includes 1733 records, including 1263 nucleotide sequences with ORFs, of these 942 have been identified as toxin-coding. The database of peptide sequences was built based on of the transcriptomics results. It contains 217 new toxins, 212 of them were detected in the T. oblongus venom by the proteomics.
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spelling pubmed-106653942023-11-22 Venom-gland transcriptomics and venom proteomics of the Tibellus oblongus spider Korolkova, Yuliya Mikov, Alexander Lobas, Anna Solovyeva, Elizaveta Surin, Alexey Andreev, Yaroslav Gorshkov, Mikhail Kozlov, Sergey Sci Data Data Descriptor The Tibellus oblongus spider is an active hunter that does not spin webs and remains highly underinvestigated in terms of the venom composition. Here, we describe venom glands transcriptome and venom proteome analysis for unveiling the polypeptide composition of Tibellus oblongus spider venom. The resulting EST database includes 1733 records, including 1263 nucleotide sequences with ORFs, of these 942 have been identified as toxin-coding. The database of peptide sequences was built based on of the transcriptomics results. It contains 217 new toxins, 212 of them were detected in the T. oblongus venom by the proteomics. Nature Publishing Group UK 2023-11-22 /pmc/articles/PMC10665394/ /pubmed/37993463 http://dx.doi.org/10.1038/s41597-023-02703-0 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Data Descriptor
Korolkova, Yuliya
Mikov, Alexander
Lobas, Anna
Solovyeva, Elizaveta
Surin, Alexey
Andreev, Yaroslav
Gorshkov, Mikhail
Kozlov, Sergey
Venom-gland transcriptomics and venom proteomics of the Tibellus oblongus spider
title Venom-gland transcriptomics and venom proteomics of the Tibellus oblongus spider
title_full Venom-gland transcriptomics and venom proteomics of the Tibellus oblongus spider
title_fullStr Venom-gland transcriptomics and venom proteomics of the Tibellus oblongus spider
title_full_unstemmed Venom-gland transcriptomics and venom proteomics of the Tibellus oblongus spider
title_short Venom-gland transcriptomics and venom proteomics of the Tibellus oblongus spider
title_sort venom-gland transcriptomics and venom proteomics of the tibellus oblongus spider
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665394/
https://www.ncbi.nlm.nih.gov/pubmed/37993463
http://dx.doi.org/10.1038/s41597-023-02703-0
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