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Protein kinase B/AKT phosphorylates hypoxia-inducible factor-3α1 in response to insulin, promoting cell growth and migration

Hypoxia-inducible factors (HIFs) are best known for their roles in the adaptation to low oxygen environments. Besides hypoxia, HIF-1/2 α-subunits are also regulated by various non-hypoxic stimuli including insulin which can act via the PI3K/protein kinase B (PKB) signaling pathway. However, with res...

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Detalles Bibliográficos
Autores principales:	Nguyen, Tran Vinh Hong, Bergmann, Ulrich, Kietzmann, Thomas, Mennerich, Daniela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665492/ https://www.ncbi.nlm.nih.gov/pubmed/38020884 http://dx.doi.org/10.3389/fcell.2023.1250000

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