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Orthosteric and allosteric modulation of human HCAR2 signaling complex

Hydroxycarboxylic acids are crucial metabolic intermediates involved in various physiological and pathological processes, some of which are recognized by specific hydroxycarboxylic acid receptors (HCARs). HCAR2 is one such receptor, activated by endogenous β-hydroxybutyrate (3-HB) and butyrate, and...

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Detalles Bibliográficos
Autores principales:	Mao, Chunyou, Gao, Mengru, Zang, Shao-Kun, Zhu, Yanqing, Shen, Dan-Dan, Chen, Li-Nan, Yang, Liu, Wang, Zhiwei, Zhang, Huibing, Wang, Wei-Wei, Shen, Qingya, Lu, Yanhui, Ma, Xin, Zhang, Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665550/ https://www.ncbi.nlm.nih.gov/pubmed/37993467 http://dx.doi.org/10.1038/s41467-023-43537-z

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