Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation

Treatment of recurrent myelodysplastic syndrome (MDS) after hematopoietic cell transplantation (HCT) remains challenging. We present a 4‐year‐old girl experiencing early MDS relapse post‐HCT treated with a multimodal strategy encompassing a second HCT and innovative targeted therapies. We underscore...

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Autores principales: Wachter, Franziska, Pikman, Yana, Bledsoe, Jacob, Kapadia, Malika, Baumeister, Susanne, Rowe, Jared, Shimamura, Akiko, Place, Andrew E., Prockop, Susan, Whangbo, Jennifer, Lehmann, Leslie, Horan, John, Pollard, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665583/
https://www.ncbi.nlm.nih.gov/pubmed/38028059
http://dx.doi.org/10.1002/ccr3.8190
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author Wachter, Franziska
Pikman, Yana
Bledsoe, Jacob
Kapadia, Malika
Baumeister, Susanne
Rowe, Jared
Shimamura, Akiko
Place, Andrew E.
Prockop, Susan
Whangbo, Jennifer
Lehmann, Leslie
Horan, John
Pollard, Jessica
author_facet Wachter, Franziska
Pikman, Yana
Bledsoe, Jacob
Kapadia, Malika
Baumeister, Susanne
Rowe, Jared
Shimamura, Akiko
Place, Andrew E.
Prockop, Susan
Whangbo, Jennifer
Lehmann, Leslie
Horan, John
Pollard, Jessica
author_sort Wachter, Franziska
collection PubMed
description Treatment of recurrent myelodysplastic syndrome (MDS) after hematopoietic cell transplantation (HCT) remains challenging. We present a 4‐year‐old girl experiencing early MDS relapse post‐HCT treated with a multimodal strategy encompassing a second HCT and innovative targeted therapies. We underscore the potential of a comprehensive treatment approach in managing recurrent pediatric MDS.
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spelling pubmed-106655832023-11-22 Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation Wachter, Franziska Pikman, Yana Bledsoe, Jacob Kapadia, Malika Baumeister, Susanne Rowe, Jared Shimamura, Akiko Place, Andrew E. Prockop, Susan Whangbo, Jennifer Lehmann, Leslie Horan, John Pollard, Jessica Clin Case Rep Case Report Treatment of recurrent myelodysplastic syndrome (MDS) after hematopoietic cell transplantation (HCT) remains challenging. We present a 4‐year‐old girl experiencing early MDS relapse post‐HCT treated with a multimodal strategy encompassing a second HCT and innovative targeted therapies. We underscore the potential of a comprehensive treatment approach in managing recurrent pediatric MDS. John Wiley and Sons Inc. 2023-11-22 /pmc/articles/PMC10665583/ /pubmed/38028059 http://dx.doi.org/10.1002/ccr3.8190 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Report
Wachter, Franziska
Pikman, Yana
Bledsoe, Jacob
Kapadia, Malika
Baumeister, Susanne
Rowe, Jared
Shimamura, Akiko
Place, Andrew E.
Prockop, Susan
Whangbo, Jennifer
Lehmann, Leslie
Horan, John
Pollard, Jessica
Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation
title Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation
title_full Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation
title_fullStr Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation
title_full_unstemmed Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation
title_short Treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation
title_sort treatment of recurrent pediatric myelodysplastic syndrome post hematopoietic stem cell transplantation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665583/
https://www.ncbi.nlm.nih.gov/pubmed/38028059
http://dx.doi.org/10.1002/ccr3.8190
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