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Stricturing Crohn's disease: what is the role of endoscopic stenting? A systematic review
BACKGROUND/AIMS: Endoscopic stenting for stricturing Crohn's disease (CD) is an emerging treatment that achieves more persistent dilatation of the stricture over time than endoscopic balloon dilatation (EBD). We aimed to explore the efficacy and safety of stenting for the treatment of CD strict...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Gastrointestinal Endoscopy
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665612/ https://www.ncbi.nlm.nih.gov/pubmed/37915191 http://dx.doi.org/10.5946/ce.2023.059 |
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author | Scotti, Giorgia Burrelli Lorenzetti, Roberto Aratari, Annalisa Lamazza, Antonietta Fiori, Enrico Papi, Claudio Festa, Stefano |
author_facet | Scotti, Giorgia Burrelli Lorenzetti, Roberto Aratari, Annalisa Lamazza, Antonietta Fiori, Enrico Papi, Claudio Festa, Stefano |
author_sort | Scotti, Giorgia Burrelli |
collection | PubMed |
description | BACKGROUND/AIMS: Endoscopic stenting for stricturing Crohn's disease (CD) is an emerging treatment that achieves more persistent dilatation of the stricture over time than endoscopic balloon dilatation (EBD). We aimed to explore the efficacy and safety of stenting for the treatment of CD strictures. METHODS: A systematic electronic literature search was performed (PROSPERO; no. CRD42022308033). The primary outcomes were technical success, efficacy, complication rate, and the need for further interventions due to reobstruction. The outcomes of partially covered self-expanding metal stents (PCSEMS) with scheduled retrieval after seven days were also analyzed. RESULTS: Eleven eligible studies were included in the review. Overall, 173 patients with CD were included in this study. Mean percentage of technical success was 95% (range, 80%–100%), short-term efficacy was 100% in all studies, and long-term efficacy was 56% (range, 25%–90%). In patients with a scheduled PCSEMS retrieval, the long-term efficacy was 76% (range, 59%–90%), the mean complication rate was 35% (range, 15%–57%), and the major complication rate was 11% (range, 0%–29%). CONCLUSIONS: Endoscopic stenting with scheduled PCSEMS retrieval may be considered a feasible second-line treatment for short CD strictures to postpone surgery. However, larger head-to-head prospective studies are needed to understand the role of stenting as an alternative or additional treatment to EBD in CD. |
format | Online Article Text |
id | pubmed-10665612 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Korean Society of Gastrointestinal Endoscopy |
record_format | MEDLINE/PubMed |
spelling | pubmed-106656122023-11-01 Stricturing Crohn's disease: what is the role of endoscopic stenting? A systematic review Scotti, Giorgia Burrelli Lorenzetti, Roberto Aratari, Annalisa Lamazza, Antonietta Fiori, Enrico Papi, Claudio Festa, Stefano Clin Endosc Systematic Review and Meta-analysis BACKGROUND/AIMS: Endoscopic stenting for stricturing Crohn's disease (CD) is an emerging treatment that achieves more persistent dilatation of the stricture over time than endoscopic balloon dilatation (EBD). We aimed to explore the efficacy and safety of stenting for the treatment of CD strictures. METHODS: A systematic electronic literature search was performed (PROSPERO; no. CRD42022308033). The primary outcomes were technical success, efficacy, complication rate, and the need for further interventions due to reobstruction. The outcomes of partially covered self-expanding metal stents (PCSEMS) with scheduled retrieval after seven days were also analyzed. RESULTS: Eleven eligible studies were included in the review. Overall, 173 patients with CD were included in this study. Mean percentage of technical success was 95% (range, 80%–100%), short-term efficacy was 100% in all studies, and long-term efficacy was 56% (range, 25%–90%). In patients with a scheduled PCSEMS retrieval, the long-term efficacy was 76% (range, 59%–90%), the mean complication rate was 35% (range, 15%–57%), and the major complication rate was 11% (range, 0%–29%). CONCLUSIONS: Endoscopic stenting with scheduled PCSEMS retrieval may be considered a feasible second-line treatment for short CD strictures to postpone surgery. However, larger head-to-head prospective studies are needed to understand the role of stenting as an alternative or additional treatment to EBD in CD. Korean Society of Gastrointestinal Endoscopy 2023-11 2023-10-24 /pmc/articles/PMC10665612/ /pubmed/37915191 http://dx.doi.org/10.5946/ce.2023.059 Text en Copyright © 2023 Korean Society of Gastrointestinal Endoscopy https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Systematic Review and Meta-analysis Scotti, Giorgia Burrelli Lorenzetti, Roberto Aratari, Annalisa Lamazza, Antonietta Fiori, Enrico Papi, Claudio Festa, Stefano Stricturing Crohn's disease: what is the role of endoscopic stenting? A systematic review |
title | Stricturing Crohn's disease: what is the role of endoscopic stenting? A systematic review |
title_full | Stricturing Crohn's disease: what is the role of endoscopic stenting? A systematic review |
title_fullStr | Stricturing Crohn's disease: what is the role of endoscopic stenting? A systematic review |
title_full_unstemmed | Stricturing Crohn's disease: what is the role of endoscopic stenting? A systematic review |
title_short | Stricturing Crohn's disease: what is the role of endoscopic stenting? A systematic review |
title_sort | stricturing crohn's disease: what is the role of endoscopic stenting? a systematic review |
topic | Systematic Review and Meta-analysis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665612/ https://www.ncbi.nlm.nih.gov/pubmed/37915191 http://dx.doi.org/10.5946/ce.2023.059 |
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