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Short salsalate administration affects cell proliferation, metabolism, and inflammation in polycystic kidney disease
Metabolic reprogramming is a driver of autosomal dominant polycystic kidney disease (ADPKD) progression and a potential therapeutic intervention route. We showed before that the AMP-associated protein kinase (AMPK) activator salsalate attenuates cystic disease progression. Here, we aim to study the...
Autores principales: | Kanhai, Anish A., Sánchez-López, Elena, Kuipers, Thomas B., van Klinken, Jan B., Dijkstra, Kyra L., van der Veen, Inge, Baelde, Hans J., Song, Xuewen, Pei, York, Mei, Hailiang, Leonhard, Wouter N., Mayboroda, Oleg A., Peters, Dorien J.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665819/ https://www.ncbi.nlm.nih.gov/pubmed/38026227 http://dx.doi.org/10.1016/j.isci.2023.108278 |
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