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Dapagliflozin alleviates renal inflammation and protects against diabetic kidney diseases, both dependent and independent of blood glucose levels

INTRODUCTION: Diabetic kidney disease (DKD) has become the leading cause of end-stage renal disease worldwide. Therefore, efforts to understand DKD pathophysiology and prevent its development at the early phase are highly warranted. METHODS: Here, we analyzed kidneys from healthy mice, diabetic mice...

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Detalles Bibliográficos
Autores principales: Cai, Anxiang, Shen, Jianxiao, Yang, Xiaoqian, Shao, Xinghua, Gu, Leyi, Mou, Shan, Che, Xiajing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665888/
https://www.ncbi.nlm.nih.gov/pubmed/38022502
http://dx.doi.org/10.3389/fimmu.2023.1205834