Cargando…

Impaired synaptic incorporation of AMPA receptors in a mouse model of fragile X syndrome

Fragile X syndrome (FXS) is the most common monogenetic cause of inherited intellectual disability and autism in humans. One of the well-characterized molecular phenotypes of Fmr1 KO mice, a model of FXS, is increased translation of synaptic proteins. Although this upregulation stabilizes in adultho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chojnacka, Magdalena, Beroun, Anna, Magnowska, Marta, Stawikowska, Aleksandra, Cysewski, Dominik, Milek, Jacek, Dziembowska, Magdalena, Kuzniewska, Bozena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Molecular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665894/ https://www.ncbi.nlm.nih.gov/pubmed/38025260 http://dx.doi.org/10.3389/fnmol.2023.1258615

Ejemplares similares

Disrupting interaction between miR-132 and Mmp9 3′UTR improves synaptic plasticity and memory in mice
por: Kuzniewska, Bozena, et al.
Publicado: (2022)

Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage
por: Chmielewska, Joanna J., et al.
Publicado: (2018)

Mitochondrial protein biogenesis in the synapse is supported by local translation
por: Kuzniewska, Bozena, et al.
Publicado: (2020)

AMPA and GABAA receptor nanodomains assemble in the absence of synaptic neurotransmitter release
por: Ramsay, Harrison J., et al.
Publicado: (2023)

Erratum: AMPA and GABAA receptor nanodomains assemble in the absence of synaptic neurotransmitter release
Publicado: (2023)

miR-132 Regulates Dendritic Spine Structure by Direct Targeting of Matrix Metalloproteinase 9 mRNA
por: Jasińska, Magdalena, et al.
Publicado: (2015)

Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes
por: Lee, Sang Hak, et al.
Publicado: (2017)

Structural Plasticity of Dendritic Spines Requires GSK3α and GSK3β
por: Cymerman, Iwona A., et al.
Publicado: (2015)

Correction: Super-resolution imaging of synaptic and Extra-synaptic AMPA receptors with different-sized fluorescent probes
por: Lee, Sang Hak, et al.
Publicado: (2017)

Hyperexcitability and Homeostasis in Fragile X Syndrome
por: Liu, Xiaopeng, et al.
Publicado: (2022)

AKAP150 Palmitoylation Regulates Synaptic Incorporation of Ca(2+)-Permeable AMPA Receptors to Control LTP
por: Purkey, Alicia M., et al.
Publicado: (2018)

Fragile X Mental Retardation Protein: To Be or Not to Be a Translational Enhancer
por: Maurin, Thomas, et al.
Publicado: (2018)

Fragile X mental retardation protein and synaptic plasticity
por: Sidorov, Michael S, et al.
Publicado: (2013)

Dysregulated Ca(2+)-Permeable AMPA Receptor Signaling in Neural Progenitors Modeling Fragile X Syndrome
por: Danesi, Claudia, et al.
Publicado: (2019)

Targeted Therapy of Cognitive Deficits in Fragile X Syndrome
por: Puścian, A., et al.
Publicado: (2022)

Impaired synaptic transmission in dorsal dentate gyrus increases impulsive alcohol seeking
por: Nalberczak-Skóra, Maria, et al.
Publicado: (2022)

Human Cerebral Cortex Proteome of Fragile X-Associated Tremor/Ataxia Syndrome
por: Holm, Katharine Nichole, et al.
Publicado: (2021)

Synaptic vesicle dynamic changes in a model of fragile X
por: Broek, Jantine A. C., et al.
Publicado: (2016)

Loss of serum response factor in mature neurons in the dentate gyrus alters the morphology of dendritic spines and hippocampus-dependent behavioral tasks
por: Nader, Karolina, et al.
Publicado: (2019)

Corrigendum: Human Cerebral Cortex Proteome of Fragile X-Associated Tremor/Ataxia Syndrome
por: Holm, Katharine Nichole, et al.
Publicado: (2021)

AMPA Receptor Activation Causes Silencing of AMPA Receptor-Mediated Synaptic Transmission in the Developing Hippocampus
por: Wasling, Pontus, et al.
Publicado: (2012)

FRAGILE X MENTAL RETARDATION PROTEIN REPLACEMENT RESTORES HIPPOCAMPAL SYNAPTIC FUNCTION IN A MOUSE MODEL OF FRAGILE X SYNDROME
por: Zeier, Zane, et al.
Publicado: (2009)

ATR protects the genome against CGG·CCG-repeat expansion in Fragile X premutation mice
por: Entezam, Ali, et al.
Publicado: (2008)

In silico, in vitro, and in vivo Approaches to Identify Molecular Players in Fragile X Tremor and Ataxia Syndrome
por: Haify, Saif N., et al.
Publicado: (2020)

Taurine regulation of short term synaptic plasticity in fragile X mice
por: El Idrissi, Abdeslem, et al.
Publicado: (2010)

Synaptic Plasticity, a Prominent Contributor to the Anxiety in Fragile X Syndrome
por: Yang, Tao, et al.
Publicado: (2016)

Homeostatic synaptic scaling: molecular regulators of synaptic AMPA-type glutamate receptors
por: Chowdhury, Dhrubajyoti, et al.
Publicado: (2018)

The role of AMPA receptors in postsynaptic mechanisms of synaptic plasticity
por: Chater, Thomas E., et al.
Publicado: (2014)

Hebbian and homeostatic synaptic plasticity of AMPA receptors in epileptogenesis
por: Curia, Giulia
Publicado: (2023)

Cingulate protein arginine methyltransferases 1 regulates peripheral hypersensitivity via fragile X messenger ribonucleoprotein
por: Wu, Cheng, et al.
Publicado: (2023)

Behavioral and Synaptic Circuit Features in a Zebrafish Model of Fragile X Syndrome
por: Ng, Ming-Chong, et al.
Publicado: (2013)

Fragile X mental retardation protein regulates trans-synaptic signaling in Drosophila
por: Friedman, Samuel H., et al.
Publicado: (2013)

Molecular Mechanisms of Synaptic Dysregulation in Fragile X Syndrome and Autism Spectrum Disorders
por: Telias, Michael
Publicado: (2019)

Ca(2+)-permeable AMPA receptors in homeostatic synaptic plasticity
por: Lee, Hey-Kyoung
Publicado: (2012)

Noelin1 Affects Lateral Mobility of Synaptic AMPA Receptors
por: Pandya, Nikhil J., et al.
Publicado: (2018)

Palmitoylation-mediated synaptic regulation of AMPA receptor trafficking and function
por: Sohn, Heesung, et al.
Publicado: (2019)

Calcineurin Mediates Synaptic Scaling Via Synaptic Trafficking of Ca(2+)-Permeable AMPA Receptors
por: Kim, Seonil, et al.
Publicado: (2014)

Fragile X syndrome and fragile X-associated disorders
por: Rajaratnam, Akash, et al.
Publicado: (2017)

Rapid, experience-dependent translation of neurogranin enables memory encoding
por: Jones, Kendrick J., et al.
Publicado: (2018)

Fragile X astrocytes induce developmental delays in dendrite maturation and synaptic protein expression
por: Jacobs, Shelley, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_dle0nactkgeskh1m9u8g516no6