Deletion of hepatic small heterodimer partner ameliorates development of nonalcoholic steatohepatitis in mice

Small heterodimer partner (SHP, Nr0b2) is an orphan nuclear receptor that regulates bile acid, lipid, and glucose metabolism. Shp(−/−) mice are resistant to diet-induced obesity and hepatic steatosis. In this study, we explored the potential role of SHP in the development of nonalcoholic steatohepat...

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Detalles Bibliográficos
Autores principales: Lee, Yoon-Kwang, Park, Jung Eun, Lee, Mikang, Mifflin, Ryan, Xu, Yang, Novak, Robert, Zhang, Yanqiao, Hardwick, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665942/
https://www.ncbi.nlm.nih.gov/pubmed/37827334
http://dx.doi.org/10.1016/j.jlr.2023.100454

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