Cargando…
Unlatching of the stem domains in the Staphylococcus aureus pore-forming leukocidin LukAB influences toxin oligomerization
Staphylococcus aureus (S. aureus) is a serious global pathogen that causes a diverse range of invasive diseases. S. aureus utilizes a family of pore-forming toxins, known as bi-component leukocidins, to evade the host immune response and promote infection. Among these is LukAB (leukocidin A/leukocid...
Autores principales: | Ilmain, Juliana K., Perelman, Sofya S., Panepinto, Maria C., Irnov, Irnov, Coudray, Nicolas, Samhadaneh, Nora, Pironti, Alejandro, Ueberheide, Beatrix, Ekiert, Damian C., Bhabha, Gira, Torres, Victor J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665946/ https://www.ncbi.nlm.nih.gov/pubmed/37802313 http://dx.doi.org/10.1016/j.jbc.2023.105321 |
Ejemplares similares
-
Genetic variation of staphylococcal LukAB toxin determines receptor tropism
por: Perelman, Sofya S., et al.
Publicado: (2021) -
Rational Design of Toxoid Vaccine Candidates for Staphylococcus aureus Leukocidin AB (LukAB)
por: Kailasan, Shweta, et al.
Publicado: (2019) -
Staphylococcus aureus Leukocidin A/B (LukAB) Kills Human Monocytes via Host NLRP3 and ASC when Extracellular, but Not Intracellular
por: Melehani, Jason H., et al.
Publicado: (2015) -
The Major Autolysin Atl Regulates the Virulence of Staphylococcus aureus by Controlling the Sorting of LukAB
por: Zheng, Xuhui, et al.
Publicado: (2022) -
Staphylococcus aureus Impairs the Function of and Kills Human Dendritic Cells via the LukAB Toxin
por: Berends, Evelien T. M., et al.
Publicado: (2019)