Cooperative lipolytic control of neuronal triacylglycerol by spastic paraplegia-associated enzyme DDHD2 and ATGL

Intracellular lipolysis—the enzymatic breakdown of lipid droplet-associated triacylglycerol (TAG)—depends on the cooperative action of several hydrolytic enzymes and regulatory proteins, together designated as lipolysome. Adipose triglyceride lipase (ATGL) acts as a major cellular TAG hydrolase and...

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Detalles Bibliográficos
Autores principales: Hofer, Peter, Grabner, Gernot F., König, Mario, Xie, Hao, Bulfon, Dominik, Ludwig, Anton E., Wolinski, Heimo, Zimmermann, Robert, Zechner, Rudolf, Heier, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665947/
https://www.ncbi.nlm.nih.gov/pubmed/37832604
http://dx.doi.org/10.1016/j.jlr.2023.100457

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