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TGFβ-induced circLTBP2 predicts a poor prognosis in intrahepatic cholangiocarcinoma and mediates gemcitabine resistance by sponging miR-338-3p

BACKGROUND & AIMS: Intrahepatic cholangiocarcinoma (iCCA) is a deadly cancer worldwide with an increasing incidence and limited therapeutic options. Therefore, there is an urgent need to open the field to new concepts for identifying clinically relevant therapeutic targets and biomarkers. Here,...

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Detalles Bibliográficos
Autores principales: Louis, Corentin, Ferlier, Tanguy, Leroux, Raffaële, Pineau, Raphaël, Desoteux, Matthis, Papoutsoglou, Panagiotis, Leclerc, Delphine, Angenard, Gaëlle, Vaquero, Javier, Macias, Rocio I.R., Edeline, Julien, Coulouarn, Cédric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665948/
https://www.ncbi.nlm.nih.gov/pubmed/38023605
http://dx.doi.org/10.1016/j.jhepr.2023.100900