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Uncoupling protein 2 modulates polarization and metabolism of human primary macrophages via glycolysis and the NF‑κB pathway

Metabolic abnormalities, particularly the M1/M2 macrophage imbalance, play a critical role in the development of various diseases, leading to severe inflammatory responses. The present study aimed to investigate the role of uncoupling protein 2 (UCP2) in regulating macrophage polarization, glycolysi...

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Detalles Bibliográficos
Autores principales: Lang, Liguo, Zheng, Dongju, Jiang, Qingjun, Meng, Ting, Ma, Xiaohu, Yang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665990/
https://www.ncbi.nlm.nih.gov/pubmed/38023353
http://dx.doi.org/10.3892/etm.2023.12282